Progress of PI3K/Akt signal pathwayon pathogenesis of Kashin-Beck disease
Kashin-beck disease(KBD)is a kind of unknown endemic osteoarticular disease,which always causes severe burdens for families.In recent years,lots of studies have explored the pathogenesis of KBD at the levels of genes and proteins with the development of the precision medicine,and found that the PI3K/Akt signal pathway had a great significance on the molecular mechanism of KBD.This article summarizes the present studies and prospects of the PI3K/Akt signal pathways on the pathogenesis of KBD,providing scientific basis to the further explorations of the pathogenesis of KBD.
NETL
NSTL
万方数据
维普
