Efficacy of sodium hyaluronate combined with diprospanin the treatment of knee osteoarthritis
Objective To explore the efficacy of sodium hyaluronate combined with diprospan in the treatment of knee osteoarthritis.Methods A total of 82 patients with knee osteoarthritis were randomly divided into 2 groups: control group (n=41) which received intra-articular injection of sodium hyaluronate, and the observation group (n=41) which received intra-articular injection of sodium hyaluronate and diprospan.The Lysholm score, KPS score 1 and 3 months after treatment and adverse reactions during treatment were recorded.Results The effective rate of observation group and control group was 92.7% and 65.9%, respectively.The effective rate was higher in the observation group than in the control group (P<0.05).Before treatment, there was no statistical significance in Lysholm scores between the two groups, while 1 and 3 months after treatment, the Lysholm scores were increased, which were higher in the observation group than in the control group (P<0.05).Before treatment, there was no statistical significance in KPS scores between the 2 groups, while 1 and 3 months after treatment, KPS scores were increased, which were higher in the observation group than in the control group (P<005).During treatment, there was no statistical significance in adverse reactions between the 2 groups (P>0.05).Conclusions Sodium hyaluronate combined with diprospan has a good curative effect on knee osteoarthritis, which can significantly improve knee function and quality of life with high safety.
sodium hyaluronatediprospanknee osteoarthritisquality of life
NETL
NSTL
万方数据
维普
