老年脑出血患者术后下肢深静脉血栓风险模型的构建
Establishment of Risk Model of Postoperative Deep Venous Thrombosis in Elderly Patients with Cerebral Hemorrhage
张莎莎 1许彬 1颜伟 2陈锦园1
作者信息
- 1. 江苏省人民医院神经外科ICU,南京 210029
- 2. 江苏省人民医院神经外科,南京 210029
- 折叠
摘要
目的 探讨老年脑出血患者术后下肢深静脉血栓(DVT)发生的危险因素,构建DVT风险评估模型.方法 选取2020年7月-2023年1月在江苏省人民医院接受手术治疗的95例老年脑出血患者作为研究对象,按照术后是否发生DVT分为DVT组(25例)和非DVT组(70例).比较两组的一般资料、术前及术中相关因素,采用单因素分析和多因素logistic回归模型分析筛选DVT发生的危险因素,构建DVT风险评估模型.结果 DVT组与非DVT组在年龄、吸烟史、高血压史、心脏病史、脑出血量及手术时间方面比较,差异均有统计学意义(P＜0.05);多因素logistic回归模型分析显示,年龄≥70岁、有吸烟史、有高血压史、有心脏病史、脑出血量≥30 mL、手术时间≥3 h是老年脑出血患者术后发生DVT的独立危险因素(P＜0.05).根据回归系数构建了 DVT风险评估模型,模型的灵敏度为88.0％,特异度为85.7％,准确度为86.3％,曲线下面积为0.938(95％CI:0.901-0.975).结论 本研究构建了一种适用于老年脑出血患者术后DVT发生的风险评估模型,具有较高的准确性和可靠性,可为临床DVT的预防和干预提供依据.
Abstract
Objective To investigate the risk factors of postoperative lower extremity deep venous thrombosis(DVT)in elderly patients with cerebral hemorrhage,and to construct a DVT risk assessment model.Methods A total of ninety five elderly pa-tients with cerebral hemorrhage who underwent surgery in Jiangsu Provincial Peoples Hospital from July 2020 to January 2023 were se-lected as the study subjects and divided into DVT group(25 cases)and non-DVT group(70 cases)according to whether DVT oc-curred or not after surgery.The general data,preoperative and intraoperative related factors of the two groups were compared,and univariate analysis and multivariate logistic regression model analysis were used to screen the risk factors for the occurrence of DVT and construct a DVT risk assessment model.Results There were significant differences in age,smoking history,hypertension history,heart disease history,cerebral hemorrhage volume and operation time between the DVT group and the non-DVT group(P＜0.05).Multivariate logistic regression model analysis showed that age ≥70 years,smoking history,hypertension history,heart disease histo-ry,cerebral hemorrhage volume ≥30 mL and operation time ≥3 h were independent risk factors of postoperative DVT in elderly pa-tients with cerebral hemorrhage(P＜0.05).The DVT risk assessment model was constructed based on the regression coefficient,with a sensitivity of 88.0％,specificity of 85.7％,accuracy of 86.3％,and area under the curve of 0.938(95％CI:0.901～0.975).Conclusion A risk assessment model suitable for postoperative DVT in elderly patients with cerebral hemorrhage was con-structed in this study,which has high accuracy and reliability and can provide the basis for the prevention and intervention of clinical DVT.
关键词
老年/脑出血/下肢深静脉血栓/风险评估模型Key words
Elderly/Cerebral hemorrhage/Lower limb deep vein thrombosis/Risk assessment model引用本文复制引用
基金项目
江苏省科技计划基础研究计划()
江苏省自然科学基金面上项目(BK20221418)
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据