国际老年医学杂志2024,Vol.45Issue(2) :199-203.DOI:10.3969/j.issn.1674-7593.2024.02.014

AIMS65评分和中性粒细胞淋巴细胞比值与老年肝硬化食管胃底静脉破裂出血患者住院期间死亡的相关性

Correlation of AIMS65 Score and Neutrophil-to-lymphocyte Ratio with Death during Hospitalisation in Elderly Patients with Ruptured Esophagogastric Vein Haemorrhage in Cirrhosis

翟恒勇 王凯 汤丽娟 肖亮 李昱江
国际老年医学杂志2024,Vol.45Issue(2) :199-203.DOI:10.3969/j.issn.1674-7593.2024.02.014

AIMS65评分和中性粒细胞淋巴细胞比值与老年肝硬化食管胃底静脉破裂出血患者住院期间死亡的相关性

Correlation of AIMS65 Score and Neutrophil-to-lymphocyte Ratio with Death during Hospitalisation in Elderly Patients with Ruptured Esophagogastric Vein Haemorrhage in Cirrhosis

翟恒勇 1王凯 1汤丽娟 1肖亮 1李昱江1
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作者信息

  • 1. 南京医科大学附属泰州人民医院消化内科,泰州 225300
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摘要

目的 评估AIMS65评分联合中性粒细胞淋巴细胞比值(NLR)预测肝硬化食管胃底静脉破裂出血(EGVB)住院死亡的可行性,旨在辅助临床进行患者管理.方法 选取2018年1月—2022年10月在南京医科大学附属泰州人民医院住院治疗的326例肝硬化EGVB患者为研究对象.根据住院期间转归情况分为死亡组33例、生存组293例.通过电子病历收集所有患者的临床资料,采用多因素logis-tic 回归法筛选肝硬化EGVB患者住院期间死亡的独立危险因素;采用ROC曲线分析入院时AIMS65评分联合NLR预测EGVB住院期间死亡的临床价值.结果 单因素分析显示,两组白蛋白、NLR、AIMS65评分差异均有统计学意义(P<0.05).多因素logistic回归分析显示,NLR、AIMS65评分是肝硬化EGVB患者院内死亡的独立危险因素(P<0.05).ROC曲线分析显示,AIMS65联合NLR预测肝硬化EGVB患者院内死亡的效能高于单一 AIMS65、NLR,预测效能最高,差异有统计学意义(P<0.05).结论 AIMS65评分联合NLR可预测肝硬化EGVB患者院内死亡风险,为此类患者危险分层以及个体化干预提供了思路.

Abstract

Objective To evaluate the feasibility of AIMS65 score combined with neutrophil-to-lymphocyte ratio(NLR)in predicting in-hospital death from esophageal and gastric variceal bleeding(EGVB)in cirrhosis in order to assist clinical patient management.Methods A total of 326 patients with EGVB due to liver cirrhosis who were hospitalized in Taizhou People's Hospital Affiliated to Nanjing Medical University from January 2018 to October 2022 were selected as the study subjects.According to the out-come during hospitalization,33 patients were divided into death group and 293 patients into survival group.The clinical data of all pa-tients were collected by electronic medical records,and multivariate logistic regression was used to screen the independent risk factors for in-hospital death in cirrhotic EGVB patients;ROC curve was used to analyze the clinical value of AIMS65 score combined with NLR at admission in predicting in-hospital death in EGVB patients.Results Univariate analysis showed that there were significant differences in albumin,NLR,and AIMS65 scores between the two groups(P<0.05).Multivariate logistic regression analysis showed that NLR and AIMS65 scores were independent risk factors for in-hospital death in cirrhotic EGVB patients(P<0.05).ROC curve analysis showed that AIMS65 combined with NLR was more effective than AIMS65 alone and NLR in predicting in-hospital death in cirrhotic EGVB patients,with the highest predictive efficacy,and the difference was statistically significant(P<0.05).Conclusion AIMS65 score combined with NLR can predict the risk of in-hospital mortality in cirrhotic EGVB patients,providing i-deas for risk stratification as well as individualized intervention in such patients.

关键词

肝硬化/食管胃底静脉破裂出血/住院死亡/风险预测

Key words

Cirrhosis/Esophageal and gastric variceal bleeding/In-hospital death/Risk prediction

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基金项目

江苏省自然科学基金(Y2020Q06)

出版年

2024
国际老年医学杂志
吉林大学

国际老年医学杂志

CSTPCD
影响因子:0.435
ISSN:1674-7593
参考文献量17
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