摘要
肌少症在老年人中常见,其患病率随增龄而增加,目前尚且缺乏有效治疗手段,故早期诊断至关重要.高灵敏度、特异度的生物标志物检测可提高肌少症的早期诊断并改善预后.本文对炎症因子类、激素相关类、氧化应激反应类、循环介质类等生物标志物与肌少症相关性的研究新进展作一综述,为肌少症的诊断、治疗及预后提供新思路、新方法.
Abstract
Sarcopenia is prevalent among the elderly.The incidence of this condition rises with advancing age,posing dan-ger and lacking effective therapeutic options.Hence,timely detection is crucial.Enhancing the ability to identify biomarkers with high sensitivity and specificity may enhance the early diagnosis and prognosis of sarcopenia.This article examines recent advancements in the investigation of the correlation between biomarkers,including inflammatory variables,hormones,oxidative stress,circulatory mediators,and sarcopenia.It offers novel concepts and techniques for the identification,management,and prediction of sarcopenia.
基金项目
国家自然科学基金(82160276)
新疆维吾尔自治区自然科学基金(2021D01C162)
维普
万方数据