国际老年医学杂志2024,Vol.45Issue(5) :554-558.DOI:10.3969/j.issn.1674-7593.2024.05.008

CT评估腹膜癌指数对老年卵巢癌术后复发转移的预测

Prognostic Value of CT Evaluation of Peritoneal Carcinoma Index in Postoperative Recurrence and Metastasis of Elderly Ovarian Cancer

周金金 于克 毛海燕 张杰
国际老年医学杂志2024,Vol.45Issue(5) :554-558.DOI:10.3969/j.issn.1674-7593.2024.05.008

CT评估腹膜癌指数对老年卵巢癌术后复发转移的预测

Prognostic Value of CT Evaluation of Peritoneal Carcinoma Index in Postoperative Recurrence and Metastasis of Elderly Ovarian Cancer

周金金 1于克 1毛海燕 1张杰1
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作者信息

  • 1. 扬州大学附属医院,扬州 225001
  • 折叠

摘要

目的 探讨CT评估腹膜癌指数(CT-PCI)对老年卵巢癌术后复发转移的预测价值.方法 选取2016年1月—2022年6月在扬州大学附属医院接受卵巢癌减灭术治疗的85例老年卵巢癌患者作为研究对象.随访至2023年12月(3例失访),经电子病历系统采集患者资料,Cox风险比例模型分析影响老年卵巢癌患者术后复发转移的因素.结果 82例老年卵巢癌患者中出现复发转移者20例;复发转移组临床分期Ⅳ期、伴有淋巴结转移、腹膜转移、脉管浸润及分化程度为低分化和未分化者占比和CA125、CEA、Ki-67阳性率、CT-PCI评分均高于无复发转移组(P<0.05);Cox风险比例模型结果显示,临床分期Ⅳ期、腹膜转移、CA125、Ki-67阳性、CT-PCI评分均为影响老年卵巢癌患者术后复发转移的独立危险因素(P<0.05).结论 CT-PCI对老年卵巢癌术后复发转移具有一定的预测价值,可作为临床术后管理指导.

Abstract

Objective To investigate the value of CT evaluation of peritoneal carcinoma index(CT-PCI)in predicting re-currence and metastasis of elderly ovarian cancer after operation.Methods A total of 85 elderly patients with ovarian cancer who re-ceived radical resection for ovarian cancer in the Affiliated Hospital of Yangzhou University from January 2016 to June 2022 were select-ed and followed up until December 2023(3 cases were lost).Patient data were collected through the electronic medical record sys-tem,Cox regression analysis was performed to analyze the factors affecting postoperative recurrence and metastasis of elderly patients with ovarian cancer.Results Recurrence and metastasis occurred in 20 of 82 elderly patients with ovarian cancer.The proportion of clinical stage Ⅳ,with lymph node metastasis,peritoneal metastasis,vascular invasion and poorly differentiated and undifferentiated,and CA125,CEA,Ki-67 positivity exrate,and CT-PCI scores in recurrent metastasis group were all higher than those in the group without recurrence and metastasis(P<0.05).Cox proportional hazards model showed that clinical stage Ⅳ,peritoneal metastasis,CA125,Ki-67 positivity rate,and CT-PCI scores were all independent risk factors affecting postoperative recurrence and metastasis in elderly patients with ovarian cancer(P<0.05).Conclusion CT-PCI has a certain predictive value for postoperative recurrence and metastasis of elderly ovarian cancer,It can be used as guidance for clinical postoperative management.

关键词

卵巢癌/CT评估腹膜癌指数/复发/转移/预测

Key words

Ovarian Cancer/CT evaluation of peritoneal carcinomatosis index/Recurrence/Transfer/Forecast

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基金项目

江苏省卫生健康委科研项目(M2021039)

出版年

2024
国际老年医学杂志
吉林大学

国际老年医学杂志

CSTPCD
影响因子:0.435
ISSN:1674-7593
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