国际老年医学杂志2024,Vol.45Issue(5) :566-570.DOI:10.3969/j.issn.1674-7593.2024.05.010

术前HALP评分对老年结直肠癌患者根治术后肠梗阻发生的预测价值

Predictive Value of Preoperative HALP Score for Postoperative Intestinal Obstruction in Elderly Patients Undergoing Radical Resection of Colorectal Cancer

孔丽丽 李翠
国际老年医学杂志2024,Vol.45Issue(5) :566-570.DOI:10.3969/j.issn.1674-7593.2024.05.010

术前HALP评分对老年结直肠癌患者根治术后肠梗阻发生的预测价值

Predictive Value of Preoperative HALP Score for Postoperative Intestinal Obstruction in Elderly Patients Undergoing Radical Resection of Colorectal Cancer

孔丽丽 1李翠1
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作者信息

  • 1. 联勤保障部队第九○四医院,无锡 214000
  • 折叠

摘要

目的 探讨术前HALP评分对老年结直肠癌患者根治术后并发肠梗阻的预测价值.方法 选取2020-2022年于联勤保障部队第九○四医院进行根治术治疗的162例老年结直肠癌患者进行回顾性分析,根据患者术后4 d内是否发生肠梗阻分为肠梗阻组(30例)和对照组(132例).比较两组临床资料,采用logistic回归分析结直肠癌术后并发肠梗阻的影响因素,ROC曲线分析术前HALP评分对结直肠癌术后并发肠梗阻的预测价值.结果 肠梗阻组的术前HALP评分及术前球蛋白(Glb)水平均低于对照组(P<0.05);多因素logistic回归分析显示,术前HALP评分、术前Glb水平均为结直肠癌术后并发肠梗阻的独立危险因素(P<0.05);ROC曲线分析显示,术前HALP评分预测结直肠癌术后并发肠梗阻的AUC为0.901(95%CI:0.842~0.976),最佳临界值为35.5分,灵敏度为92.2%,特异度为87.6%.结论 术前HALP评分是老年结直肠癌患者术后并发肠梗阻的危险因素,对术后并发肠梗阻具有较高的预测价值.

Abstract

Objective To investigate the predictive value of preoperative HALP score for postoperative intestinal obstruction in elderly patients undergoing radical resection of colorectal cancer.Methods A total of 162 elderly patients with colorectal cancer who underwent radical resection in the 904th Hospital of the PLA Joint Logistic Support Force from 2020 to 2022 were selected for ret-rospective analysis.The patients were divided into an intestinal obstruction group(30 cases)and a control group(132 cases)accord-ing to whether intestinal obstruction occurred 4 d after operation.The clinical data of the two groups were compared,logistic regression was used to analyze the influencing factors of intestinal obstruction after colorectal cancer surgery,and ROC curve was used to analyze the predictive value of preoperative HALP score for intestinal obstruction after colorectal cancer surgery.Results The preoperative HALP score and preoperative globulin(Glb)level in the intestinal obstruction group were lower than those in the control group(P<0.05).Multivariate logistic regression analysis showed that the preoperative HALP score and preoperative Glb level were independent risk factors of intestinal obstruction after colorectal cancer surgery(P<0.05).ROC curve analysis showed that,the AUC of preoper-ative HALP score for the prediction of intestinal obstruction after colorectal cancer surgery was 0.901(95%CI:0.842-0.976),the optimal cut-off value was 35.5 scores,the sensitivity was 92.2%,and the specificity was 87.6%.Conclusion Preoperative HALP score is a risk factor of postoperative intestinal obstruction in elderly patients with colorectal cancer,and has a high predictive value for postoperative intestinal obstruction.

关键词

血红蛋白/白蛋白/淋巴细胞/血小板/肠梗阻

Key words

Hemoglobin/Albumin/Lymphocyte/Platelets/Intestinal obstruction

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基金项目

江苏省卫生健康委员会项目(2022036)

出版年

2024
国际老年医学杂志
吉林大学

国际老年医学杂志

CSTPCD
影响因子:0.435
ISSN:1674-7593
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