Objective To explore the intervention effect of health education based on the concept of Oren's self-care theory in elderly patients with acute ischemic stroke.Methods A total of 138 elderly acute ischemic stroke patients admitted to Handan Central Hos-pital from November 2021 to November 2023 were selected and randomly separated into two groups using a random number table method,each had 69 cases.The control group received routine health education,while the research group received health education based on the concept of Oren's self-care theory on the top of control group.Rehabilitation compliance,self-care ability,limb function,10-meter walk test(10MWT),Timed up and go test(TUGT),healthy behavior,and self-care ability were compared between two groups.Results The com-pliance rate of research group was higher than that in control group(P<0.05).After the intervention,the scores of the modified Barthel index,upper limb and lower limb Fugl-Meyer assessment scale,exercise of self-care agency and health promotion lifestyle profile scale in both groups were higher than before the intervention(P<0.05),and the indicators of the research group were higher than those in the con-trol group(P<0.05).After intervention,the 10MWT and TUGT of both groups were lower than before intervention(P<0.05),and the indicators of the research group were lower than those in the control group(P<0.05).Conclusion Health education based on the concept of Oren's self-care theory can improve the rehabilitation compliance,self-care ability,limb function,and self-care ability of elderly acute is-chemic stroke patients,reduce 10MWT and TUGT,and promote healthy behavior.