Cementum plays a crucial role in linking periodontal and dental tissues and maintaining tooth root stabili-ty.Regenerating cementum is essential for functional periodontal tissue regeneration.It is a significant focus in tissue engineer-ing.Periodontal disease,prevalent among the middle-aged and elderly,can severely impact overall health.Effective periodontal tissue regeneration is vital for enhancing the elderly's health and quality of life.Despite the progress,the lack of ideal scaffold materials and methods makes cementum regeneration a persistent challenge.This review discusses the current state of cementum tissue engineering materials and addresses existing challenges,providing a foundation for future scaffold material development.
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