Predictive value of epicardial fat thickness for left ventricular reverse remodeling after radiofrequency ablation in atrial fibrillation patients with left ventricular hypertrophy
Objective To investigate the predictive value of epicardial fat thickness(EFT)for left ventricular reverse re-modeling after radiofrequency ablation in patients with left ventricular hypertrophy.Methods A total of 50 patients with atrial fibrilla-tion admitted to Shanxi Bethune Hospital from June 2021 to September 2023 were retrospectively collected.The clinical data of the pa-tients were collected by electronic medical records.EFT was examined by echocardiography.The patients were divided into groups ac-cording to whether reverse remodeling was achieved.Univariate and multivariate logistic regression models were used to analyze the fac-tors of postoperative left ventricular reverse remodeling.ROC curve was used to analyze the predictive value of EFT.Results A total of 28 patients who did not achieve reverse remodeling were included in the control group,and 22 patients who achieved reverse remodeling were included in the reverse remodeling group.There were significant differences in age,atrial fibrillation classification,duration of at-rial fibrillation,left atrial diameter(LAD),left ventricular end-diastolic diameter,left ventricular end-diastolic diameter index(LVE-DI),neutrophil to lymphocyte ratio(NLR),high-sensitivity C-reactive protein(hsCRP),platelet distribution width(PDW),red cell distribution width,fibrinogen to albumin ratio(FAR)and EFT between the two groups(P＜0.05).Multivariate logistic regres-sion analysis showed that EFT,LAD,LVEDI,NLR,hsCRP,PDW and FAR were independent factors for left ventricular reverse re-modeling(P＜0.05).The cut-off value of EFT for predicting postoperative left ventricular reverse remodeling was 0.848,sensitivity was 95.5％,specificity was 89.3％,and AUC was 0.937(95％CI:0.868-0.983).Conclusion EFT has a high predictive value for postoperative left ventricular reverse remodeling in patients with left ventricular hypertrophy.
万方数据
维普
