国际老年医学杂志2025,Vol.46Issue(1) :110-113.DOI:10.3969/j.issn.1674-7593.2025.01.022

中药多糖对心肌缺血再灌注损伤的保护作用研究

Research progress on protective effect of polysaccharide from traditional Chinese medicine on myocardial ischemia-reperfusion injury

孙倩 费虹天 赵思琪 张丽娇 费瑞
国际老年医学杂志2025,Vol.46Issue(1) :110-113.DOI:10.3969/j.issn.1674-7593.2025.01.022

中药多糖对心肌缺血再灌注损伤的保护作用研究

Research progress on protective effect of polysaccharide from traditional Chinese medicine on myocardial ischemia-reperfusion injury

孙倩 1费虹天 2赵思琪 3张丽娇 1费瑞4
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作者信息

  • 1. 长春师范大学生命科学学院,长春 130032
  • 2. 吉林大学基础医学院,长春 130021
  • 3. 吉林大学中日联谊医院新民院区,长春 130021
  • 4. 吉林大学基础医学院,长春 130021;吉林大学中日联谊医院新民院区,长春 130021
  • 折叠

摘要

心肌缺血再灌注损伤(MIRI)是缺血性心脏病中常见的病理生理过程,是加重心肌损伤的重要原因,在老年人群中极为常见.它不仅危害老年人的健康,同时也给社会带来很大压力与经济负担.多糖是一种广泛存在于动物、植物和微生物中的天然大分子,是有益于人体健康的高活性物质.其中,利用现代科技手段从中药中提取出来的多糖,因其安全高效而广泛应用于医药领域,且在改善多种心血管疾病过程中扮演了重要角色.本文对中药多糖在MIRI中的作用及机制作一综述,为进一步开展老年心血管疾病的治疗提供更详尽的资料.

Abstract

Myocardial ischemia-reperfusion injury(MIRI)is a prevalent pathophysiological process associated with ische-mic heart disease and significantly exacerbates myocardial damage,particularly in the elderly population.This condition not only poses serious risks to individual health but also brings creates substantial societal and economic burdens.Polysaccharides,natural macromole-cule found in animals,plants and microorganisms,serve as active substance that confer various health benefits.Among these,polysac-charides extracted from traditional Chinese medicine(TCM)through modern scientific techniques have gained prominence in the medi-cal field due to their safety and high efficiency,playing a vital role in the management of various cardiovascular diseases.This paper,provides a comprehensive review of the role and mechanisms of TCM-derived polysaccharide in MIRI,aiming to furnish valuable in-sights for the future treatment of cardiovascular diseases in the elderly.

关键词

多糖/缺血性心脏病/心肌缺血再灌注损伤

Key words

Polysaccharide/Ischemic heart disease/Myocardial ischemia-reperfusion injury

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出版年

2025
国际老年医学杂志
吉林大学

国际老年医学杂志

影响因子:0.435
ISSN:1674-7593
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