Mechanism of Drug Resistance and Treatment of Staphylococcus aureus
Staphylococcus aureus(S.aureus)is a widespread Gram-positive zoonotic bacterial pathogen causing a variety of infections including septicemia and endocarditis.Due to its rapid spread,high pathogenicity and increasing drug resistance,S.aureus has become a serious threat to global public health and animal breeding.This has created an urgent need for an improved understanding of S.aureus mechanism-of-resistance and the discovery of drugs for potential targets.Therefore,this review summarized the mechanism-of-action and mechanism-of-resistance of anti-S.aureus in current clinical use,to provide new perspectives and references for the prevention and treatment of bacterial resistance and new drug development.
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