首页|伏立康唑致氯气中毒患者肝损伤1例

伏立康唑致氯气中毒患者肝损伤1例

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目的 分析伏立康唑引起药物性肝损伤的原因、机制及影响因素,为临床药物性肝损伤的诊断与治疗提供参考.方法 临床药师充分应用药学专业知识,参与1例氯气中毒后继发真菌感染患者的治疗过程.结果 临床药师结合用药史及药物作用特点,协助医师查找和判断急性肝损伤的原因、发病机制及治疗方案,最终患者预后良好.结论 临床药师参与诊疗,对患者进行用药监护,可降低不良反应的危害,提高临床用药的安全性.
A Case Report of Hepatic Injury in a Patient with Chlorine Poisoning Caused by Voriconazole
Objective To analyze the causes,mechanisms and influencing factors of drug-induced liver injury caused by voriconazole,and to provide a reference for the diagnosis and treatment of drug-induced liver injury.Methods Following chlorine gas poisoning,a patient developed a secondary fungal infection.Clinical pharmacists assisted in the patient's care.Results By combining the patient's medical history with the properties of the prescription,clinical pharmacists helped physicians diagnose,evaluate,and treat acute liver injury.Conclusion Clinical pharmacists participating in diagnosis,treatment and drug monitoring can reduce the harm of adverse reactions and improve the safety of clinical drugs.

voriconazoleliver injuryblood drug concentrationadverse reactionanti-infection

田丹丽、麻小英、刘江波

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天津市第一中心医院,天津 300192

天津医科大学,天津 300052

伏立康唑 肝损伤 血药浓度 不良反应 抗感染

2024

国外医药(抗生素分册)
中国医药集团总公司四川抗菌素工业研究所,中国医学科学院医药生物技术研究所

国外医药(抗生素分册)

影响因子:0.852
ISSN:1001-8751
年,卷(期):2024.45(3)
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