高校化学工程学报2024,Vol.38Issue(3) :475-482.DOI:10.3969/j.issn.1003-9015.2024.03.015

自循环发酵过程周期性开关操控的设计和分析

On/off operation design and analysis of a self-cycling fermentation process

吴思辰 翟持
高校化学工程学报2024,Vol.38Issue(3) :475-482.DOI:10.3969/j.issn.1003-9015.2024.03.015

自循环发酵过程周期性开关操控的设计和分析

On/off operation design and analysis of a self-cycling fermentation process

吴思辰 1翟持1
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作者信息

  • 1. 昆明理工大学 化学工程学院,云南 昆明 650500
  • 折叠

摘要

针对乙醇间歇发酵生产速率低、劳动强度大,连续发酵会带来基质损失,甚至可能导致系统失稳的问题,探讨了一种能自动进行周期开关操控的自循环发酵(SCF)方案,并期望通过理论分析与设计来提高发酵过程的生产强度,同时消除产物抑制诱导系统失稳.具体地,从连续发酵模型稳定性分析出发,借助最优周期控制(OPC)理论给出 SCF强化生产速率的必要性判据;进一步研究发现乙醇产物抑制作用会导致连续发酵系统失稳,并可有效缓解产物抑制作用,消除产物诱导失稳问题.模拟结果表明,生物乙醇的SCF生产模式可以缩短批次发酵时间、避免系统失稳.

Abstract

Ethanol fermentation by batch mode has low production rate and enormous labor requirement,whereas substrate run-away could be substantial by continuous mode,with further possibility that the instabilities might lead to washout and cause the process to shut down.A self-cycling fermentation(SCF)approach was proposed in this study with auto on/off circulation,and the system was designed and analyzed to obtain performance enhancement and stability.The study started with an experimentally verified continuous ethanol fermentation model,and an optimal periodic control(OPC)theory was adopted to formulate optimal condition.The results indicate that the inhabitation effects of the fermentation products can lead to continuous system instability.The simulation results reveal that SCF can shorten fermentation period and avoid system instability.

关键词

产物抑制失稳/最优周期控制/自循环发酵/提质增效

Key words

end-production inhibition induced instability/optimal periodic control(OPC)/self-cycling fermentation(SCF)/process intensification

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基金项目

云南省基础研究计划(202001AU070048)

出版年

2024
高校化学工程学报
浙江大学

高校化学工程学报

CSTPCD北大核心
影响因子:0.591
ISSN:1003-9015
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