Research Progress on the Propagation Process and Control Technology of ARGs in Wastewater
The widespread use of antibiotics is rapidly increasing the prevalence of antibiotic-resistant bacteria(ARB)and their associated antibiotic-resistant genes(ARGs),posing a significant environmental challenge and high health risk to the global population.Wastewater treatment plant(WWTP)effluents containing untreated antibiotics are key hotspots for the generation and spread of ARGs and ARBs,with serious consequences for human and animal health,as well as threats to ecological security.This paper reviews the occurrence and risk of ARGs in wastewater and enumerates the main pathways and potential impacts of ARGs transmission.Statistics on the reduction techniques of ARGs by bibliometric means are also presented to provide important insights for effective control of ARGs.In addition,treatment processes for removing ARGs from wastewater are critically discussed.Finally,the topical issues of ARGs prompted by composite pollution are summarized to provide future research directions and solutions for composite pollution.