Objective:To investigate the prevalence of maternal adverse childhood experiences(ACEs)and the intergenerational effect on children's neuropsychological development,so as to provide scientific basis for pro-moting the physical and mental health development of children.Methods:A cross-sectional study was conducted within four kindergartens and two health center outpatient clinics in Beihai City.The maternal prevalence of AC-Es and the neuropsychological development of their children were investigated using the simplified Chinese ver-sion of the International Scale of Adverse Childhood Experiences(SC-ACE-IQ)and the parental version of Ages&Stages Questionnaires,Third Edition(ASQ-3),respectively.A multiple logistic regression model was applied to analyze the association between maternal ACEs and neuropsychological development of children.Results:The top three most common ACEs for mothers were community violence(36.9%),domestic violence(32.3%),and physical neglect(22.5%),and 65.6%of them experienced at least one ACE.Multiple logistic regression anal-ysis showed that maternal emotional neglect experienced during childhood increased the risk of offspring's devel-opmental delays in problem-solving(OR=3.8,95%CI:1.2-12.0,P=0.023),communication(OR=6.9,95%CI:2.3-20.3,P<0.001),and gross motor movements(OR=3.8,95%CI:1.5-9.7,P=0.005).Conclusion:Maternal ACEs among preschool children in Beihai has certain local characteristics.Maternal emotional neglect may affect the developmental delays in children,including problem solving,communication,and gross motor movements.