Research progress on the role of iron metabolism on thrombosis
Iron metabolism refers to the dynamic balance of iron metabolism in the body in the aspects of ab-sorption,transport,utilization,loss,circulation,regulation and storage.Iron metabolism plays an important role in maintaining normal physiological activities.Iron deficiency and iron overload may occur when iron metabo-lism is unbalanced.There is evidence that thrombosis is associated with iron deficiency and iron overload result-ing from an imbalance in iron metabolism,but its mechanism of action in venous thrombosis has not been eluci-dated.This paper describes the relevant mechanisms of iron metabolism absorption,metabolism and regulation,summarizes the effects of iron deficiency,iron overload and other iron homeostasis imbalances on thrombosis,and focuses on its mechanism of action in the process of thrombosis,hoping to provide new ideas for clinical pre-vention and treatment of thrombosis by taking iron metabolism as an entry point.
iron metabolismiron deficiencyiron overloadthrombosis
万方数据
维普
