华南地区马拉色菌毛囊炎的流行病学研究:一项多中心研究
The epidemiology of Malassezia folliculitis in South China:a multicenter study
何小娟 1郑冬燕 2吴维轩 2廖万清 3左玉辉 4李秋云 4周怡彤 5汤露露 6黄国梅 6梁丽山 7刘千龙 7吴玲艳 8韦丽娟 8韦珠荣 9张建玲 10彭智鹏 11钟春明 11谭元清 11吴国琼 12李鑫垒 13何绍 13梁少光 14梁明寰 14陆兴山 15谢治 16曹存巍 17刘慧2
作者信息
- 1. 广西医科大学第一附属医院皮肤性病科,南宁 530021;广西真菌病防控科技创新合作基地,南宁 530021;广西艾滋病防治研究重点实验室,南宁 530021
- 2. 广西医科大学第一附属医院皮肤性病科,南宁 530021
- 3. 防城港市万清皮肤病与真菌病防控研究院,防城港 538000
- 4. 桂平市人民医院,桂平 537200
- 5. 桂林医学院附属医院皮肤科,桂林 541001
- 6. 广西医科大学第二附属医院,南宁 530007
- 7. 百色市皮肤病防治院,百色 533000
- 8. 南宁市第二人民医院,南宁 530031
- 9. 南宁市第八人民医院,南宁 530003
- 10. 广西壮族自治区工人医院,南宁 530213
- 11. 南宁市第四人民医院,南宁 530023
- 12. 北流市人民医院,北流 537400
- 13. 玉林市皮肤病医院,玉林 537000
- 14. 藤县人民医院,梧州 543300
- 15. 南宁市武鸣区更昌医院,南宁 530199
- 16. 广西壮族自治区人民医院,南宁 530021
- 17. 广西医科大学第一附属医院皮肤性病科,南宁 530021;广西真菌病防控科技创新合作基地,南宁 530021;防城港市万清皮肤病与真菌病防控研究院,防城港 538000
- 折叠
摘要
目的:为了明确广西马拉色菌毛囊炎(MF)的流行病学特征及心理社会影响.方法:收集2022年9月至2023年8月广西14家医院诊治的MF患者,进行真菌学检查和菌种鉴定,同时采用问卷调查表进行易感因素和心理社会影响调查.结果:共收集219例患者,男女比例1.01∶1,主要发生在18～25岁,春、夏季节高发.面部是常见的受累部位.油性皮肤、多汗、痤疮和偏好辛辣食物患者所占比例均超过50%.80.4%患者认为学习、工作受到影响.半数以上的患者自觉焦虑、没有自信,并且女性显著多于男性(P＜0.05).最常见的病原体是合轴马拉色菌(35.4%),菌种分布在性别、身体部位和季节之间存在明显差异(P＜0.05).结论:MF的面部经常受到影响,油性皮肤、多汗、痤疮和饮食习惯是主要诱发因素,患者的生活质量、心理情绪不容忽视,合轴马拉色菌是本地区MF的优势菌种,菌种分布在性别、身体部位和季节之间存在较大差异.
Abstract
Objective:To define the epidemiological characteristics and psychosocial impact of Malasseziafollic-ulitis(MF)in Guangxi.Methods:From September 2022 to August 2023,cases diagnosed with MF were collect-ed for mycological examination and species identification in 14 hospitals in Guangxi,while predisposing factors and psychosocial effects were investigated using a questionnaire.Results:Among the 219 cases,the male-to-fe-male ratio was 1.01:1,which mainly occurred in the age of 18-25 years,with a high incidence in spring and sum-mer seasons.The face was a common site of involvement.The proportion of patients with oily skin,excessive sweating,acne and a preference for spicy food was over 50%.80.4%patients felt that their studies and work were affected.More than half of the patients felt anxious and had no self-confidence,and it was significantly more common in women than in men(P＜0.05).The most common pathogen of MF was M.sympodialis(35.4%),and the distribution of different species varied considerably according to gender,body parts and seasons(P＜0.05).Conclusion:The face is often affected by MF.Oily skin,excessive sweating,acne and dietary habits are the main predisposing factors.The quality of life and psychoemotional well-being in patients cannot be ignored.M.sympo-dialisis the predominant species of MF in this region,and the distribution of species varies considerably in terms of gender,body parts and seasons.
关键词
马拉色菌毛囊炎/临床特征/诱发因素/心理社会影响/菌种分布Key words
Malassezia folliculitis/clinical characteristic/predisposing factors/psychosocial impact/distribution of Malasseziaspecies引用本文复制引用
基金项目
国家重点研发计划(2022YFC2504805)
广西创新研究团队项目(2020GXNSFGA238001)
南宁市青秀区科技计划(2020016)
出版年
2024
国家科技期刊平台
NSTL
万方数据