Clinical effect of drug therapy and nerve block combined with spinal adjustment for the treatment of zoster-associated pain
Objective To explore the clinical effect of drug therapy and nerve block combined with spinal adjustment for the treatment of zoster-associated pain(ZAP).Methods A total of 97 ZAP patients were randomly divided into observation group(49 cases)or control group(48 cases).Patients in the control group received drug therapy combined with nerve block therapy,based on which the observation group received spinal adjustment(head and neck,thoracic vertebra disk and lumbosacral segments)for treatment.Visual Analog Scale(VAS)for pain,Self-Rating Anxiety Scale(SAS),Self-Rating Depression Scale(SDS),and Pittsburgh Sleep Quality Index(PSQI)were used to evaluate states of pain,anxiety,depression,and sleep quality,respectively.Scores of VAS for pain,SAS,SDS,and PSQI before treatment,1 and 3 months after treatment,and clinical efficacy after treatment,as well as the incidence rate of adverse reactions during treatment were compared between patients of the two groups.Results There were statistically significant differences in scores of VAS for pain,SAS,SDS,and PSQI between patients of the two groups(P<0.05),and the aforementioned scores exhibited a tendency of decrease with time prolonging(P<0.05),as well as there was interaction effect between grouping and time(P<0.05);furthermore,the observation group exhibited lower scores of VAS for pain,SAS,SDS,and PSQI as compared with the control group(P<0.05).After 3 months of treatment,the total effective rate of the observation group was higher than that of the control group(P<0.05).During treatment,no severe adverse reaction in patients of the two groups occurred,and the incidence rates of severe headache,dizziness,constipation were lower in the observation group than in the control group(P<0.05).Conclusion Drug therapy and nerve block combined with spinal adjustment therapy can effectively ameliorate ZAP patients'states of pain,anxiety,depression,and sleep quality,exerting favorable clinical effects,with relatively high safety.
国家科技期刊平台
NSTL
万方数据
