Optimization of Extraction Process of Tougu Tincture by Box-Behnken Response Surface Method
[Objective]This study aims at optimizing the extraction process of Tougu tincture.[Methods]Taking the curcumin content and the comprehensive score of total solids of the preparation as the evaluation indicators,single factor experiment was conducted with ethanol volume fraction,soaking time,percolation flow rate as with affecting fac-tors.On the basis of the single factor experiment,experiments designed according to Box-Behnken response surface method were conducted to optimize the extraction process of Tougu tincture and then verify it.[Results]The optimal ex-traction process was with these following conditions:60%as the ethanol volume fraction,36 h as soaking time,2 ml/min as percolation flow rate.[Conclusion]The model established by Box-Behnken response surface method is relatively ac-curate.The optimal extraction process of Tougu tincture is stable and realiable,which provides a reference for the quali-ty control of Tougu tincture.
Tougu tinctureBox-Benken response surface methodcurcuminextraction process