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强化水解在抗生素生产废水预处理中的应用研究

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抗生素生产废水中过高的抗生素浓度会影响生物反应器的处理性能,同时会加速抗生素耐药基因(ARG)的增殖与扩散.利用水解对抗生素生产废水进行预处理,可使废水中目标抗生素的化学键断裂、官能团脱落,水解产物的抗菌活性大大降低,利于后续生物处理.通过改变溶液pH值及环境温度可以加速水解的过程,达到强化水解的效果.在分析不同抗生素水解机理的基础上,总结了近年来热水解和酸、碱水解强化降解不同抗生素的研究进展.
Research progress of enhanced hydrolysis in pretreatment of antibiotic production wastewater
Wastewater from antiobitic production contains high concentration of antibiotic,which may affect the treatment performance of bioreactor and accelerate the proliferation and diffusion of antibiotic resistance gene(ARG).Using hydrolysis to pretreat antibiotic production wastewater can break the chemical bond of the antibi-otic,make the functional group fall off,decrease the antibacterial activity of the hydrolysis product,which is ben-eficial to the subsequent biological treatment.Through changing the pH value of the solution and the environment temperature,the hydrolytic process can be accelerated,and then,the enhanced hydrolysis effect is obtained.Based on the analysis of hydrolysis mechanism of different antibiotics,the research progress of enhanced degra-dation of different antibiotics by pyrohydrolysis,acid hydrolysis and alkaline hydrolysis in recent years were sum-marized.

enhanced hydrolysisantibacterial activitypyrohydrolysisalkaline hydrolysisacid hydrolysisantibiotic production wastewater

冯新桐、马成进、朱兆亮

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山东建筑大学 市政与环境工程学院,济南 250101

日照市公用事业管理服务中心,山东 日照 276800

强化水解 抗菌活性 热水解 碱水解 酸水解 抗生素生产废水

2024

工业用水与废水
东化工程科技股份有限公司

工业用水与废水

CSTPCD
影响因子:0.649
ISSN:1009-2455
年,卷(期):2024.55(3)
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