Objective To evaluate the perioperative safety and long-term outcomes of laparoscopic radical resection for carcinoma of colon and rectum(CRC)combined with intraoperative microwave ablation(MWA)versus laparoscopic hepatectomy in treating liver metastases.Methods Fifty-nine patients undergoing laparoscopic surgery for CRC liver metastases were retrospectively analyzed,divided into a group undergoing laparoscopic radical resection combined with MWA(n=31)and a group undergoing combined laparoscopic hepatectomy(n=28).We compared intraoperative and postoperative complications,disease-free survival(PFS),and overall survival(OS)between the groups,identifying factors influencing patient survival.Results Compared to MWA,laparoscopic hepatectomy involved longer surgery times and more intraoperative bleeding(P＜0.05).No significant difference was found in postoperative complications between the groups(P＞0.05).The hepatectomy group showed longer PFS and OS(P＜0.05).Multivariate COX regression analysis identified the combination with laparoscopic MWA,multiple liver metastases,and metastasis diameter＞3 cm as independent risk factors for poorer PFS and OS(P＜0.05).Conclusion Laparoscopic radical resection combined with hepatectomy for CRC liver metastases,compared to combination with intraoperative MWA,demonstrates similar rates of complications with superior long-term survival outcomes.
关键词
结直肠癌肝转移/腹腔镜结肠癌根治/腹腔镜肝切除/微波消融
Key words
colorectal cancer hepatic metastases/laparoscopic colorectal cancer radical resection/laparoscopic hepatectomy/microwave ablation
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