Objective To investigate the risk factors affecting the number of coronary lesion branches in patients with atrial fibrillation(AF)complicated with coronary artery disease(CAD).Methods A total of 330 patients with AF complicated with CAD were selected as research subjects.According to the number of vascular lesion branches,the patients were divided into 1-vascular lesion branch group(n=122),2-vascular lesion branch group(n=95)and 3-vascular lesion branch group(n=113).The following items were compared among three groups,including gender,age,smoking history,drinking history,heart failure,hypertension,diabetes mellitus,chronic obstructive pulmonary disease(COPD),cerebrovascular history,dyslipidemia,peripheral artery disease,chronic renal failure,body mass index(BMI),uric acid,creatinine,total cholesterol(TC),triglycerides(TG),high-density lipoprotein(HDL-C),low-density lipoprotein cholesterol(LDL-C),fasting blood glucose,NT Pro BNP,CHA2DS2-VASc score,cardiac function grade,and orally taken medication before hospitalization.Differentiated indicators were incorporated into ordered logistic multivariate regression to analyze the risk factors affecting the number of coronary artery lesion branches in patients with AF combined with CAD.Results When compared with 1-vascular lesion branch group,the proportion of males,LDL-C and fasting blood glucose were significantly increased in 3-vascular lesion branch group(P＜0.05).The proportion of diabetes in 2-vascular lesion branch group was increased(P＜0.05).Ordered logistic regression analysis showed that males were 1.94 times the risk of developing multiple vascular lesion branches of females(P=0.004),and the risk of developing multiple vascular lesion branches was gradually increased for every 1 mmol/L increase in LDL-C(P＜0.001).Conclusion LDL-C is an independent risk factor for multiple vascular lesion branches in AF.When compared to females,males have a stronger correlation with multiple coronary vascular lesion branches than females have.
维普
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