Objective To investigate risk factors of rheumatoid arthritis(RA)complicated with tuberculosis(TB)infection in Guizhou region.Methods A total of 103 patients with RA were selected as research subjects.According to TB infection status,the patients were divided into simple RA group(n=71)and RA combined with TB group(n=32).General information,degree of RA disease,past medication use and other laboratory test results were compared between two groups.Multivariate logistic regression analysis was performed on above factors with statistically differentiated differences to identify risk factors for RA combined with TB infection.Results When compared with simple RA group,RA combined with TB group showed the increases in erythrocyte sedimentation rate(ESR)and C-reactive protein(CRP,P＜0.05),and there were statistically significant differences in the use of tumor necrosis factor inhibitor(TNFi)and a history of TB infection(P＜0.05).Bi nary logistic regression analysis suggested that elevated CRP and ESR,use of TNFi and previous history of TB infection were independent risk factors for TB infection in RA patients.Conclusion Elevated CRP and ESR,use of TNFi and previous history of TB infection are risk factors for RA combined with TB infection in Guizhou region.
维普
万方数据