Objective To explore the factors related to sarcopenia in elderly male inpatients with chronic diseases.Methods A total of 96 male inpatients with chronic diseases were enrolled.The general clinical data was documented,including gender,age,body mass index(BMI),education level,living habits(smoking history and drinking history,chronic diseases(hypertension,diabetes,coronary heart disease,chronic obstructive pulmonary disease,stroke),and drug types.Fasting blood samples of the patients after admission were collected to detect C reactive protein(CRP),hemoglobin(Hb),total protein(TP),albumin(ALB),prealbumin(PAB),fasting plasma glucose(FPG),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),high LDL-C(HDL-C),blood urea nitrogen(BUN),and serum creatinine(Scr).Glomerular filtration rate(eGFR)was estimated.Nutritional status was assessed by Mini-Nutritional Assessment-Short form(MNA-SF).Depressive symptom was evaluated by the 15-item Geriatric Depression Scale(GDS-15).According to the consensus of Asian Working Group for Sarcopenia(AWGS),dual energy X-ray absorptiometry was used to assess skeletal muscle mass(ASM)and fat mass(FM)of four limbs.Electronic grip strength tester was used to evaluate grip strength.Body function was assessed by 6-m daily pace.According to the diagnostic criteria,the patients were divided into sarcopenia(n=65)and non-sarcopenia(n=31)groups.The clinical data were compared between two groups.Multivariate regression analysis was used to analyze the factors related to sarcopenia in elderly male inpatients with chronic diseases.Results There were significant differences in age,BMI,limb ASM index(ASMI),grip strength,walking speed,FM,nutritional score,depression score,ALB,PAB,Hb,HDL-C,and TG/HDL-C ratio between Sarcopenia and non-Sarcopenia groups(P＜0.05).Logistic multivariate regression analysis showed that TG/HDL-C ratio,FM,ALB,and BMI had a regression association with the occurrence of sarcopenia in elderly inpatients with chronic diseases(P＜0.05).Conclusion Increased TG/HDL-C ratio,high fat content,low albumin,and low BMI are related to the occurrence of sarcopenia in elderly male inpatients with chronic diseases.Maintaining good nutritional status may help to reduce the occurrence of sarcopenia in the elderly.
维普
万方数据
