首页|红细胞输注新生儿住院期间发生并发症的危险因素分析

红细胞输注新生儿住院期间发生并发症的危险因素分析

Analysis of risk factors for complications of newborns who underwent red blood cell transfusion during hspitalization

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目的 分析红细胞输注(RBCT)新生儿住院期间发生并发症的危险因素.方法 收集RBCT治疗的306例新生儿临床资料,根据住院期间是否发生并发症分为并发症组和无并发症组,记录两组患儿一般情况(性别,胎龄,出生体质量,单/多胎,Apgar评分)、住院情况(住院时间,机械通气时间,胃肠外营养时间)和红细胞输注相关情况(RBCT前Hb值,出生后第1周医源性失血量,首次RBCT日龄,每次RBCT量,累计RBCT量,累计RBCT次数);采用logistic回归分析,观察RBCT治疗新生儿住院期间发生并发症的危险因素.结果 RBCT治疗的306例新生儿,住院期间并发症发生率35.29%(108/306);胎龄、出生体质量、性别、机械通气时间、出生后第1周医源性失血量、住院时间、首次RBCT日龄、每次RBCT量、累计RBCT次数及累计RBCT量是RBCT新生儿住院期间发生并发症的相关危险因素,P<0.05;logistic分析显示,机械通气时间及出生后第1周医源性失血量是RBCT新生儿住院期间发生并发症的独立危险因素,P<0.01.结论 机械通气时间长及支气管肺发育不良是新生儿住院期间RBCT治疗常见并发症,出生后第1周时的医源性失血量为独立危险因素.
Objective To analyze the risk factors of the complications of newborns who underwent red blood cell transfusion(RBCT)during hospitalization.Methods Clinical data of 306 newborns treated with RBCT were collected.These newborns were divided into complication and complication-free groups based on whether the complications occurred during hospitalization.The information of two groups of the newborns was documented,including general information(gender,gestational age,body weight at birth,single/multiple pregnancy,Apgar score),hospitalization(length of hospital stay,mechanical ventilation time,parenteral nutrition time)and RBCT-related information(Hb value before RBCT,the amount of iatrogenic blood loss in the first week after birth,day age of the first RBCT,RBCT amount/time,cumulative RBCT amount and cumulative RBCT times).Logistic regression analysis was conducted to observe the risk factors for the complications of the newborns treated with RBCT during the hospitalization.Results The incidence of complications of 306 newborns treated with RBCT during hospitalization was 35.29%(108/306).Fetal age,body weight at birth,gender,mechanical ventilation time,the amount of iatrogenic blood loss in the first week after birth,length of hospital stay,day age of the first RBCT,RBCT amount/time,cumulative RBCT amount and cumulative RBCT times and cumulative RBCT amount were the related risk factors for the complications of the newborns who underwent RBCT during hospitalization(P<0.05).Conclusion Long mechanical ventilation time and bronchopulmonary dysplasia are common complications of the newborns who underwent RBCT during hospitalization,and the amount of iatrogenic blood loss in the first week after birth is an independent risk factor.

newbornanemiared blood cell transfusioncomplicationrisk factors

蔡姣、赵珣、李君、陈茂琼

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贵州医科大学附属医院新生儿科,贵州贵阳 550004

贵州医科大学临床医学院,贵州贵阳 550004

黄冈市中心医院新生儿科,湖北黄冈 438000

新生儿 贫血 红细胞输注 并发症 危险因素

贵州医科大学附属医院院级临床研究课题(2021)

2021-GMHCT-001

2024

贵州医科大学学报
贵阳医学院

贵州医科大学学报

CSTPCD
影响因子:0.827
ISSN:2096-8388
年,卷(期):2024.49(5)
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