Effect of hyperbaric oxygen therapy combined with trunk control training at different stages on cognitive and motor rehabilitation in patients with ischemic stroke
Effect of hyperbaric oxygen therapy combined with trunk control training at different stages on cognitive and motor rehabilitation in patients with ischemic stroke
Objective To explore the effect of hyperbaric oxygen therapy combined with trunk control training at different stages on the rehabilitation of patients with ischemic stroke. Methods A total of 116 patients with ischemic stroke were randomly divided into a control group and an observation group. Both groups received thrombolytic therapy. The control group received trunk control training after hyperbaric oxygen intervention,while the observation group received trunk control training simultaneously with hyperbaric oxygen intervention. Both groups were treated for 4 weeks. Before and after the intervention,the Mini-Mental State Examination ( MMSE ) was used to evaluate patients 'cognitive function,the National Institutes of Health Stroke Scale ( NIHSS ) was used to assess neurological deficits,the Berg Balance Scale ( BBS) was used to evaluate balance ability,the Sheikh Trunk Control Scale ( Sheikh) was used to assess trunk control ability,the Fugl-Meyer Assessment Scale ( FMA) was used to evaluate limb function,and the Functional Independence Measure ( FIM) was used to assess patients' functional independence. Five milliliters of peripheral venous blood were collected before and after the intervention to detect levels of nerve growth factor,neuron-specific enolase,and myelin basic protein in both groups. Results After the intervention,MMSE scores increased and NIHSS scores decreased in both groups compared to pre-intervention levels,with the observation group showing higher MMSE scores and lower NIHSS scores than the control group ( P<0.05 ).Post-intervention BBS and Sheikh scores were higher than pre-intervention scores in both groups,with the observation group scoring higher than the control group (P<0.05). FMA and FIM scores increased after the intervention in both groups,with the observation group scoring higher than the control group (P<0.05). Serum nerve growth factor levels were higher,while neuron-specific enolase and myelin basic protein levels were lower post-intervention compared to pre-intervention in both groups,with the observation group showing higher nerve growth factor and lower neuron-specific enolase and myelin basic protein levels than the control group (P<0.05). Conclusion Hyperbaric oxygen therapy combined with simultaneous trunk control training is beneficial for the recovery of cognitive function and balance motor function in patients with ischemic stroke.
关键词
缺血性脑卒中/高压氧/躯干控制训练/神经损伤/认知功能
Key words
ischemic stroke/hyperbaric oxygen/trunk control training/nerve injury/cognitive function
维普
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