Prevalence and risk factors of hyperuricemia among 7 323 bus drivers
Objective To investigate the prevalence of hyperuricemia(HUA)and identify risk factors among bus drivers in Guiyang.Methods A cross-sectional study of 7 323 bus drivers,categorizing participants into HUA and normal uric acid(NUA)groups were conducted.Anthropometric measurements,blood pressure,and biochemical parameters were compared between groups.Univariate analysis identified potential risk factors,followed by multivariate logistic regression analysis of statistically significant variables.Results The overall prevalence of HUA was 33.52％(2,455/7,323),with rates of 37.00％in males and 8.42％in females.Higher prevalence rates were observed among males,young adults(20-29 years),and individuals with elevated body mass index(BMI,P＜0.05).The HUA group demonstrated significantly higher values for height,systolic blood pressure(SBP),diastolic blood pressure(DBP),white blood cell(WBC),low density lipoprotein cholesterol(LDL),triglyceride(TG),total cholesterol(TC),fasting plasma glucose(FPG),serum creatinine(Scr),carcinoembryonic antigen(CEA),alanine aminotransferas(ALT),aspartate aminotransferase(AST),and albumin(ALB)compared to the NUA group(P＜0.05).Univariate analysis showed that male,low age(20-29 years old),female≥50 years old,overweight,high WBC,increased high density lipoprotein cholesterol(HDL),LDL,TG,TC,FPG,Scr,CEA,ALT,AST,and ALB were the influencing factors of HUA in bus drivers(P＜0.05).Multivariate analysis identified male gender,age 20-29 years,female age ≥50 years,overweight status,elevated WBC,dyslipidemia(low HDL,high LDL,high TG),elevated FPG,high Scr,and increased liver function parameters(ALT,AST,ALB)as independent risk factors for HUA(P＜0.05).Conclusion Bus drivers in Guiyang demonstrate a high prevalence of HUA.Young adult age,male gender,postmenopausal female status,overweight,elevated WBC,and metabolic abnormalities represent independent risk factors for HUA development.
bus drivershyperuricemiastatus of diseaserisk factors
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