首页|拟南芥转录因子HAT1负调控盐胁迫分子机制研究

拟南芥转录因子HAT1负调控盐胁迫分子机制研究

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土壤盐碱化是目前全球农业面临的主要环境挑战之一,为使植物在盐碱地上更好地生长,开展植物盐胁迫响应机制的研究具有重大意义.植物特有的同源结构域-亮氨酸拉链(HD-ZIP)家族转录因子HAT1在拟南芥中调控多种胁迫应答,到目前为止,HAT1是否参与调控植物对盐胁迫的响应尚不清楚.文章围绕转录因子HAT1在拟南芥响应盐胁迫中的调控作用展开研究,证明了 EIN3-HAT1-CSDs分子模块可以调控植物对盐胁迫的响应,以期拓展盐胁迫的分子调控网络.盐胁迫诱导EIN3的积累,EIN3抑制HAT1的表达,进而削弱HAT1对下游基因CSD1与CSD2的转录抑制,使抗氧化系统得以激活并清除过量的活性氧,从而增强植株的盐耐受能力.该信号通路为通过分子育种提高植物盐耐受性提供了 一个新的潜在靶点.
Molecular mechanism of Arabidopsis transcription factor HAT1 negatively regulating salt stress
Soil salinity is one of the major environmental challenges facing global agriculture today,and it is of great importance to conduct research on salt stress response mechanisms in order to make plants grow better.The plant-specific homologous structural domain-leucine zipper(HD-ZIP)family transcription factor HAT1 regulates multiple stress responses in Arabidopsis,and so far,it is not clear whether HAT1 is involved in regulating plant responses to salt stress.This paper focuses on the regu-latory role of HAT1 in response to salt stress in Arabidopsis,with the aim of expanding the molecular regulatory network of salt stress.This study demonstrates that the EIN3-HAT1-CSDs molecular module regulates the plant response to salt stress.Salt stress induces the accumulation of EIN3,which inhib-ites the expression of HAT1,thereby weakening the transcriptional inhibition of HAT1 on downstream genes CSD1 and CSD2 and activating the antioxidant system to remove excess reactive oxygen species to enhance the salt tolerance of plants.This signaling pathway provides a new potential target for im-proving plant salt tolerance through molecular breeding.

salt stressHAT1CSDtranscriptional regulation

方可、李佳凤、张大伟

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四川大学生命科学学院/生物资源与生态环境教育部重点实验室,四川成都 610065

盐胁迫 HAT1 CSD 转录调控

国家自然科学基金国家自然科学基金

3207021332270258

2024

广州大学学报(自然科学版)
广州大学

广州大学学报(自然科学版)

影响因子:0.293
ISSN:1671-4229
年,卷(期):2024.23(2)
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