We studied the effect of different particle sizes(the coarsest,coarse,medium and fine)on the baicalin content and total solid yield of Shuidonggua Painkilling Tincture extracted by cold soak.Baicalin was determined by high performance liquid chromatography,and the total solid yield was measured by loss on drying method.The ba-icalin content and total solid yield were taken as indicators to optimize the particle size for the preparation of Shui-donggua Painkilling Tincture.The results showed that the baicalin content and total solid yield of the tincture pre-pared from the coarsest powder were the highest,reaching 416.1 μg/mL and 18.08％,respectively.Different parti-cle sizes have different effect on the baicalin content and total solid yield of Shuidonggua Painkilling Tincture.
维普
万方数据