理气健脾煮丸制备工艺研究
Preparation process of the boiled pill for regulating qi and invigorating the spleen
胡娟 1陈晓兰 1杜林飞 1谢树才1
作者信息
- 1. 贵州中医药大学 药学院,贵州 贵阳 550025
- 折叠
摘要
目的:研究理气健脾煮丸的处方及制备工艺.方法:以溶散时间和成型性为指标,考察煮丸中淀粉量、拐枣液、崩解剂及干燥条件对煮丸崩解时限的影响,结合橙皮苷溶出量,选择最适服用方法.结果:理气健脾煮丸制备工艺:陈皮、魔芋粉、淀粉均过8 号筛以等比例混合,加入58%的拐枣液(相对密度为1.305)于80℃和药制备湿颗粒,加入19%的NaHCO3 迅速混匀制软材,最后制丸并于50℃干燥1h;将煮丸加入沸水中溶散,在水温降至55℃后最适合服用.结论:理气健脾煮丸的制备工艺稳定可行,符合传统中医药理论的要求.
Abstract
We studied the prescription and preparation process of the boiled pill for regulating qi and invigorating the spleen.Taking the dissolution time and formability as indexes,the effect of the amount of starch,the Hovenia acerba liquid,the disintegrant and the drying time on the disintegration time of the boiled pill were investigated,and the optimal administration method was selected according to the dissolution of hesperidin.The preparation process of the boiled pills;tangerine peel,konjac flour and starch were mixed in equal proportions after passing through No.8 sieve,and 58％ Hovenia acerba liquid with a relative density of 1.305 was added to prepare wet granules at 80℃,19％ NaHCO3 was added and mixed rapidly to make soft material,and finally the pills were prepared and dried at 50℃ for 1 h.Adding the boiled pills to boiling water to dissolve and disintegrate,and it is best to take after the wa-ter temperature drops to 55℃.The preparation process of the boiled pills for regulating qi and invigorating the spleen is stable and feasible,in line with the requirements of traditional Chinese medicine theory.
关键词
理气健脾/煮丸/制备工艺/溶出/橙皮苷Key words
regulating qi and invigorating the spleen/boiling pill/preparation process/dissolution/hesperidin引用本文复制引用
基金项目
国家苗药工程技术研究中心能力提升(黔科合中引地[2023]006)
贵州省高层次创新型人才(黔科合平台人才-GCC[2023]037)
出版年
2024
NETL
NSTL
万方数据