The correlation between sensory quality and conventional chemical composition of flue-cured tobacco samples with different ranks from 33 different producing areas was analyzed by using factorial analysis and canonical correlation analysis to provide the scientific basis for raw material selection of fluecured tobacco. The results showed that increasing total sugar and reducing sugar content or reducing plant alkaloid and total nitrogen content could improve smoking scores of aftertaste, moist degree, irritancy,quality and volume of aroma, volatility and offensive odor significantly and decrease taste strength and smoke concentration, reducing potassium content or increasing nitrogen content could decrease smoking scores of aftertaste, moist degree, irritancy, quality and volume of aroma, volatility and offensive odor.The combined factorial and canonical correlation analysis can eliminate the effect of multi-colinearity in groups, so its analysis result is of accuracy and reliability.