[Objective]The ecological factors affecting the growth of Lonicera macranthoides and its geographical distribution were explored to provide scientific basis for the site selection,planning and construction of suitable cultivation areas and the utilization of plant resources.[Method]The information of 1 242 distribution samples of L.macranthoides in China were collected,and 58 ecological factors were integrated.The MaxEnt(maximum entropy)model was used to screen the dominant ecological factors affecting the suitability distribution of L.macranthoides.Combined with ArcGIS,the potential suitable distribution area of L.macranthoides in China was predicted.[Result]The MaxEnt model had high accuracy and reliability for predicting the potential suitable distribution area of L.macranthoides(AUC=0.971).The ecological factors affecting the distribution of L.macranthoides included precipitation in November,coldness index,precipitation in May,soil type,altitude,precipitation in April,isotherm,precipitation in the driest month,slope,annual average temperature range,average temperature in September,precipitation in March,average temperature in August and precipitation in October.The main ecological factors were precipitation in November,coldness index and precipitation in May,with contribution rates of 35.4%,21.6%and 17.5%,respectively.According to the comprehensive evaluation grade of suitability,it was divided into four categories:the most suitable area,the middle suitable area,the low suitable area and the unsuitable area.The potential distributions of L.macranthoides were concentrated in the south of Qinling Mountains,including Guizhou,Chongqing,Hunan,Guangxi,Guangdong,Jiangxi,Fujian,Zhejiang,Taiwan and Shaanxi.The most suitable distribution areas included central and eastern Guizhou,northern Guangxi,western and a small part of southern Hunan,southwestern Hubei,southern Chongqing,southeastern Sichuan and a small part of northeastern Guangdong,and the intersection of Fujian,Jiangxi,Zhejiang and Anhui.[Conclusion]The dominant ecological factors affecting the suitability distribution of L.macranthoides are the precipitation in November,cold index and precipitation in May.L.macranthoides mainly distributes in the south of Qinling Mountains.The most suitable distribution areas are central and eastern Guizhou,northern Guangxi,southern Chongqing and the intersection of Fujian,Jiangxi,Zhejiang and Anhui.