Royal jelly is a thick,milky white secretion from the palatine glands of young worker bees.As a natural bee product,it finds wide application in various fields,including food and health care products.One of the unique components of royal jelly is 10-hydroxy-2-decenoic acid(10-HDA),a medium-chain unsaturated fatty acid.10-HDA possesses several active functions,such as antibacterial,anti-inflammatory,anti-tumor,blood sugar regulation,blood lipid control,and anti-radiation properties.The extraction of 10-HDA from royal jelly can be efficiently achieved through physical adsorption or organic solvent treatment.Additionally,10-HDA can be synthesized by various chemical reactions using substances such as 8-hydroxyoctanal and 1,8-octanediol.In recent years,utilizing microorganisms for 10-HDA production has gained significant attention owing to its low cost and low pollution characteristics.This method has become a research hotspot.This article provides a summary of the physicochemical properties,physiological active functions,and different methods of 10-HDA production.Furthermore,it briefly discusses the advantages and disadvantages of these production methods and highlights the existing problems and prospects to offer valuable reference and information for further in-depth research on 10-HDA.
10-hydroxy-2-decenoic acidphysical and chemical propertiesphysiological activityextraction methodssynthesis methods
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