摘要
目的:分析研究CT动脉增强分数联合血清NLR、CRP对失代偿期肝硬化患者预后的评估价值.方法:选取2019年4月至2022年4月汕头市潮阳区大峰医院收治的120例失代偿期肝硬化患者作为研究对象,对患者进行1年随访,以死亡为终点事件,将患者分为生存组(n=84)与死亡组(n=36).以多因素Logistic回归分析CT动脉增强分数及血清NLR、CRP与失代偿期肝硬化患者预后的关系,并绘制ROC曲线分析CT动脉增强分数联合血清NLR、CRP对失代偿期肝硬化患者预后的预测价值.结果:多因素Logistic回归分析显示,HAEF升高(OR=1.941)、H/S升高(OR=1.815)、PTA降低(OR=2.100)、ALB降低(OR=2.008)、NLR升高(OR=2.079)及CRP水平升高(OR=2.134)均是失代偿期肝硬化患者预后的独立危险因素(P<0.05);ROC曲线分析结果显示HAEF、H/S、NLR、CRP水平及联合检测的曲线下面积(AUC)分别为0.862、0.808、0.831、0.933、0.989,联合检测优于单一检测(P<0.05).结论:CT动脉增强分数联合血清NLR、CRP对失代偿期肝硬化患者预后具有较好的评估价值.
Abstract
Objective:To evaluate the value of CT arterial enhancement fraction combined with serum NLR and CRP in the prognosis of patients with decompensated cirrhosis.Methods:A total of 120 patients with decompensated cirrhosis admitted to Dafeng Hospital,Chaoyang District,Shantou City from April 2019 to April 2022 were selected as the study objects.The patients were followed up for 1 year.Taking death as the end event,the patients were divided into survival group(n=84)and death group(n=36).Multivariate Logistic regression was used to analyze the relationship between CT arterial enhancement score,serum NLR and CRP and prognosis of patients with decompensated cirrhosis,and ROC curve was drawn to analyze the predictive value of CT arterial enhancement fractioncombined with serum NLR and CRP for prognosis of patients with decompensated cirrhosis.Results:Multivariate Logistic regression analysis showed that increased HAEF(OR=1.941),increased H/S(OR=1.815),decreased PTA(OR=2.100),decreased ALB(OR=2.008),increased NLR(OR=2.079)and increased CRP(OR=2.134)were independent risk factors for prognosis of decompensated cirrhosis patients(P<0.05).ROC curve analysis results showed that the levels of HAEF,H/S,NLR,CRP and AUC of combined detection were 0.862,0.808,0.831,0.933,0.989,respectively,and combined detection was superior to single detection(P<0.05).Conclusion:CT arterial enhancement fraction combined with serum NLR and CRP has a good value in evaluating the prognosis of patients with decompensated cirrhosis.
NETL
NSTL
万方数据