Observation on the effect of troxerutin combined with rehabilitation physiotherapy in the treatment of ischemic stroke
Objective:To investigate the clinical efficacy of troxerutin combined with rehabilitation physiotherapy in the treatment of ischemic stroke(IS).Methods:A total of 150 patients with IS admitted to our hospital from January 2021 to January 2023 were selected,and divided into control group and observation group by random number table method,with 75 cases in each group.The control group received routine rehabilitation physiotherapy intervention,and the observation group was treated with troxerutin on the basis of the control group.Both groups were treated continuously for 12 days.The clinical efficacy of the two groups was compared.The National Institutes of Health Stroke Scale(NIHSS)score,Barthel index(BI),serum microRNA-137(miR-137),miR-155,C-reactive protein(CRP)and interleukin-6(IL-6)levels were recorded before and after treatment,and the incidence of adverse reactions in the two groups was analyzed.Result:The total effective rates of the observation group and the control group were 93.3%(70/75)and 80.0%(60/75),respectively,with a significant difference(P<0.05).After treatment,the NIHSS scores of the two groups were lower than those before treatment,and the observation group was lower than the control group(all P<0.05).After treatment,the BI of the two groups were higher than those before treatment,and the observation group was higher than the control group(all P<0.05).After treatment,the levels of serum miR-137 in the two groups were higher than those before treatment,and the observation group was higher than the control group(all P<0.05).After treatment,the levels of serum miR-155 in the two groups were lower than those before treatment,and the observation group was lower than the control group(all P<0.05).After treatment,the levels of serum CRP and IL-6 in the two groups were lower than those before treatment,and those in the observation group were lower than the control group(all P<0.05).The incidence of adverse reactions in the observation group was significantly lower than that in the control group(6.67%vs 18.67%,P<0.05).Conclusions:The clinical effect of troxerutin combined with rehabilitation physiotherapy in the treatment of IS patients is better.
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