To explore the influence of Baduanjin method based on the theory of"Producing Yang by moving"on frailty,depression and inflammatory mediators during chemotherapy in elderly patients with malignant tumors
Objective:To explore the influence of Baduanjin method based on the theory of"Producing Yang by moving"on frailty,depression and inflammatory mediators during chemotherapy in elderly patients with malignant tumors.Methods:using convenience sampling,To select 81 cases of elderly patients with malignant tumors admitted to Department of Oncology,a tertiary hospital in Guangdong Province,from January 2022 to December 2022.And using the random number method,Eighty-one elderly chemotherapy patients with malignancy were simply randomly divided into two groups,Among them,41 cases were in the control group and 40 cases in the intervention group,The control group maintained its previous daily activities,The intervention group underwent 12 weeks of Baduanjin intensive training on the basis of the control group.The researchers compared the changes of frailty level(FP),depression status(SDS score),and inflammatory mediator(C-reactive protein)between the two groups before the Baduanjin exercise intervention,after the sixth week of the intervention and after the end of the twelfth week of the intervention.Results:A total of 81 patients were included.After 6 weeks of the Baduanjin intervention,There was no significant difference in the level of frailty between the intervention group and the control group(P>0.05),However,after 12 weeks of Baduanjin training,the level of frailty in the intervention group decreased significantly,There was a significant difference in the level of frailty between the two groups(P<0.05);In the intervention group,the depression of the patients in the intervention group continued to decrease during the 6 weeks and 12 weeks of Baduanjin exercise,and the difference in depression was statistically significant compared with the control group(P<0.05);After the exercise intervention at week 6 and week 12 of Baduanjin training,the levels of inflammatory mediators in the intervention group were lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion:Baduanjin can improve the level of frailty,depression and inflammation indicators in elderly patients with malignant tumors during chemotherapy,and can be promoted and practiced in elderly patients with malignant tumors during chemotherapy.
Producing Yang by movingBaduanjinchemotherapy induced frailtydepressioninflammatory mediator