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中草药组合物缓解乳腺增生的临床评价

Clinical evaluation of a Chinese herbal medicine composition for relieving breast hyperplasia

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目的:评价中草药组合物对乳腺增生症状的改善作用.方法:通过专家手诊、视觉模拟评分法(VAS)、综合医院焦虑/抑郁情绪测量表(HADS)及彩超等评价122例乳腺增生患者服用中草药组合物前、服用中三个月和停服后一个月乳房疼痛、乳腺肿块及焦虑/抑郁情绪的改善程度.结果:中草药组合物能明显减轻乳房疼痛程度且具有延续性(P<0.05);服用中草药组合物后乳房内肿块的大小、质地、分布范围以及受试者的情绪均有所改善,且与基线相比具有统计学差异(P<0.05);彩超结果表明,中草药组合物对乳腺增生有很好的治疗作用.结论:中草药组合物能有效改善乳腺增生的症状,受试者在停服中草药组合物后能感受到中草药组合物效果的延续,即使略有下降,但也优于未服用中草药组合物时的情况.
Objective:To evaluate the improvement of the symptom of mammary gland hyperplasia by Traditional Chinese herbal composition.Methods:The improvement of breast pain,breast mass and anxiety/depression in 122 patients with breast hyperplasia were evaluated by expert hand diagnosis,visual analogue scale(VAS),hospital anxiety/depression scale(HADS)and color doppler ultrasound before,during and one month after taking Chinese herbal composition.Results:Chinese herbal medicine composition could significantly reduce the degree of breast pain with continuity(P<0.05).The size,texture,distribution range of the breast masses and the mood of the subjects were improved after taking the herbal composition,and the differences were statistically significant compared with baseline(P<0.05).The results of color doppler ultrasound showed that the Chinese herbal composition had a good therapeutic effect on mammary gland hyperplasia.Conclusion:The Chinese herbal composition can effectively improve the symptoms of mammary gland hyperplasia.The subjects could feel the continuation of the effect of the Chinese herbal composition after they stopped taking the Chinese herbal composition,even if it was slightly decreased,but it was better than the situation without taking the Chinese herbal composition.

breast hyperplasiatraditional Chinese medicine compositionVAS scoresbreast pain

杜磊、李玲孺、王炳英、杜志云、谢琦

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广州市第一人民医院,广东广州 510180

北京中医药大学中医学院,北京 102488

广东工业大学生物医药学院,广东广州 510006

乳腺增生 中草药组合物 VAS评分 乳腺疼痛

国家自然科学基金面上项目

21272043

2024

广州医科大学学报
广州医学院

广州医科大学学报

影响因子:0.47
ISSN:2095-9664
年,卷(期):2024.52(2)
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