Diagnostic value of rapid on-site evaluation combined with EBUS-TBLB for peripheral pulmonary malignant diseases
Objective:To explore the diagnostic value of rapid on-site evaluation(ROSE)combined with endobronchial ultrasound transbronchial lung biopsy(EBUS-TBLB)for peripheral pulmonary malignant diseases.Methods:A retrospective analysis was performed on 190 patients with peripheral pulmonary lesions≤30 mm in diameter who underwent EBUS-TBLB examination in the National Center for Respiratory Medicine,the First Affiliated Hospital of Guangzhou Medical University from January 2021 to June 2022.According to whether ROSE examination was performed,they were divided into ROSE group(50 cases)and non-ROSE group(140 cases).The overall diagnostic rate of the two groups was compared,and the effects of the location of the lung lobe,the diameter of the lesion,the position of the ultrasonic probe in the lesion and the distance from the lesion to the pleura on the diagnostic rate of the two groups were analyzed.Results:ROSE combined with EBUS-TBLB can improve the diagnostic rate of peripheral lung malignant tumors(84.00%vs 60.71%,P=0.003).In lesions with a diameter of 21-30 mm,the diagnostic rate of ROSE group was significantly higher than that of non-ROSE group(85.29%vs 64.13%,P=0.022).ROSE could significantly improve the diagnostic rate of tumor lesions surrounded by ultrasound probe(90.32%vs 62.34%,P=0.004).The diagnostic rate of ROSE group was significantly higher than that of non-ROSE group in lesions≤15 mm from the pleura(95.24%vs 60.76%,P=0.003).Conclusion:ROSE can significantly improve the diagnostic rate of EBUS-TBLB for peripheral malignant tumors of the lung,and has more obvious advantages in lesions with a diameter of 21-30 mm,intermediate type of ultrasound image,and a distance from the pleura≤15 mm.
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