D-二聚体、三酰甘油联合脐血流参数预测子痫前期患者母婴不良结局的价值
The value of D-dimer,triglyceride combined with umbilical blood flow parameters in predicting maternal and fetal adverse outcomes in patients with preeclampsia
严海燕 1彭建良 1李春晓1
作者信息
- 1. 东莞市妇幼保健院产科,广东 东莞 523000
- 折叠
摘要
目的:探讨D-二聚体(D-D)、三酰甘油(TG)联合脐血流参数预测子痫前期患者母婴不良结局的价值.方法:收集2019年12月至2023年12月本院收治的子痫前期患者143例,按母婴结局分为不良结局组(n=68)和非不良结局组(n=75).比较两组D-D、TG水平及脐动脉收缩期峰值流速与舒张末期流速(S/D)比值,分析D-D、TG及脐动脉S/D比值判断母婴不良妊娠结局的价值.结果:不良结局组D-D、TG水平及脐动脉S/D比值均高于非不良结局组(均P<0.05).多因素Logistic回归分析显示,D-D、TG水平及S/D比值异常升高是子痫前期患者母婴不良结局的危险因素(均P<0.05).D-D+TG+S/D比值联合检测判断子痫前期患者母婴不良结局的AUC值为0.846(P<0.001),高于单项或两项指标联合检测的AUC值.结论:子痫前期患者发生母婴不良结局的风险较高,监测D-D、TG水平及脐动脉S/D比值对判断不良妊娠结局具有较高的准确性.
Abstract
Objective:To explore the value of D-dimer(D-D),triglyceride(TG)combined with umbilical blood flow parameters in predicting maternal and fetal adverse outcomes in patients with preeclampsia.Methods:A total of 143 patients with preeclampsia admitted to our hospital from December 2019 to December 2023 were collected and divided into adverse outcome group(n=68)and non-adverse outcome group(n=75)according to maternal and infant outcomes.The levels of D-D and TG,and the ratio of peak systolic velocity to end diastolic velocity(S/D)of umbilical artery were compared between the two groups,and the value of D-D,TG and umbilical artery S/D ratio in determining maternal and infant adverse pregnancy outcomes was analyzed.Results:The levels of D-D,TG and umbilical artery S/D ratio in the adverse outcome group were higher than those in the non-adverse outcome group(all P<0.05).Multivariate logistic regression analysis showed that abnormal increase levels of D-D,TG and S/D ratio were risk factors for maternal and infant adverse outcomes in preeclampsia patients(all P<0.05).The AUC value of combined detection of D-D+TG+S/D ratio in determining maternal and infant adverse outcomes in preeclampsia patients was 0.846(P<0.001),which was higher than the AUC values of single or combined detection of two indicators.Conclusion:Patients with preeclampsia have a higher risk of adverse maternal and infant outcomes.It has a high accuracy in determining the adverse pregnancy outcomes by monitoring the levels of D-D,TG,and umbilical artery S/D ratio.
关键词
D-二聚体/三酰甘油/母婴结局/子痫前期/脐血流Key words
D-dimer/triacylglycerol/maternal and infant outcome/preeclampsia/umbilical blood flow引用本文复制引用
出版年
2024
NETL
NSTL
万方数据