The value of D-dimer,triglyceride combined with umbilical blood flow parameters in predicting maternal and fetal adverse outcomes in patients with preeclampsia
Objective:To explore the value of D-dimer(D-D),triglyceride(TG)combined with umbilical blood flow parameters in predicting maternal and fetal adverse outcomes in patients with preeclampsia.Methods:A total of 143 patients with preeclampsia admitted to our hospital from December 2019 to December 2023 were collected and divided into adverse outcome group(n=68)and non-adverse outcome group(n=75)according to maternal and infant outcomes.The levels of D-D and TG,and the ratio of peak systolic velocity to end diastolic velocity(S/D)of umbilical artery were compared between the two groups,and the value of D-D,TG and umbilical artery S/D ratio in determining maternal and infant adverse pregnancy outcomes was analyzed.Results:The levels of D-D,TG and umbilical artery S/D ratio in the adverse outcome group were higher than those in the non-adverse outcome group(all P<0.05).Multivariate logistic regression analysis showed that abnormal increase levels of D-D,TG and S/D ratio were risk factors for maternal and infant adverse outcomes in preeclampsia patients(all P<0.05).The AUC value of combined detection of D-D+TG+S/D ratio in determining maternal and infant adverse outcomes in preeclampsia patients was 0.846(P<0.001),which was higher than the AUC values of single or combined detection of two indicators.Conclusion:Patients with preeclampsia have a higher risk of adverse maternal and infant outcomes.It has a high accuracy in determining the adverse pregnancy outcomes by monitoring the levels of D-D,TG,and umbilical artery S/D ratio.
D-dimertriacylglycerolmaternal and infant outcomepreeclampsiaumbilical blood flow
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