首页|缺铁性贫血孕妇的中医体质分布及影响因素研究

缺铁性贫血孕妇的中医体质分布及影响因素研究

Study on the Distribution of Traditional Chinese Medicine Constitution in Pregnant Women with Iron Deficiency Anemia and Its Influencing Factors

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[目的]分析缺铁性贫血(iron deficiency anemia,IDA)孕妇的中医体质分布规律及相关影响因素,为中医药防治妊娠期IDA提供指导方案.[方法]纳入109例符合条件的妊娠期IDA患者,收集孕妇的一般资料、中医体质鉴别结果和相关实验室指标,包括血清铁蛋白(Fer)、血红蛋白(Hb)及平均红细胞体积(MCV).对IDA孕妇的中医体质分布规律及相关影响因素、妊娠结局进行统计分析.[结果](1)109例IDA孕妇中医体质以偏颇质为主,有60例(55.05%),各体质分布人数和比例从高到低依次为:平和质49例(44.95%)>湿热质13例(11.93%)>阳虚质12例(11.01%)>阴虚质11例(10.09%)>气虚质10例(9.17%)>气郁质 9例(8.26%)>血瘀质3例(2.75%)>痰湿质2例(1.83%).(2)不同体质类型IDA孕妇的Hb和MCV水平比较,差异均无统计学意义(P>0.05),但湿热质IDA孕妇的Fer水平显著高于平和质(P<0.01),湿热质IDA孕妇发生羊水混浊的概率显著高于平和质及其他偏颇体质(P<0.05).[结论]湿热质是IDA孕妇最常见的偏颇体质,其次是阳虚质、阴虚质和气虚质,湿热质可能是IDA孕妇的易感体质,此体质类型IDA孕妇的Fer水平显著高于平和质,而其发生羊水混浊的概率显著高于平和质及其他偏颇体质.
Objective To investigate the distribution of traditional Chinese medicine(TCM)constitution in pregnant women with iron deficiency anemia(IDA)and its related influencing factors,so as to provide a reference for the TCM prevention and treatment of IDA in pregnancy.Methods A total of 109 eligible patients with IDA during pregnancy were included in the study.The general data of pregnant women,the TCM constitution types and relevant laboratory indicators including serum ferritin(Fer),hemoglobin(Hb)and mean corpuscular volume(MCV)were collected.Statistical analyses were conducted on the distribution of TCM constitution types of IDA pregnant women and its related influencing factors as well as the pregnancy outcomes.Results(1)The 109 IDA pregnant women were predominated by biased constitution types,accounted for 60 cases(55.05%).The distribution of the constitution types of 109 IDA pregnant women was as follows:balanced constitution(49 cases,44.95%)>damp-heat constitution(13 cases,11.93%)>yang deficiency constitution(12 cases,11.01%)>yin deficiency constitution(11 cases,10.09%)>qi deficiency constitution(10 cases,9.17%)>qi stagnation constitution(9 cases,8.26%)>blood stasis constitution(3 cases,2.75%)>phlegm-damp constitution(2 cases,1.83%).(2)Comparison of Hb and MCV levels in IDA pregnant women with various constitution types showed no statistically significant differences(P>0.05),but Fer level in IDA pregnant women with damp-heat constitution was significantly higher than that in IDA pregnant women with balanced constitution(P<0.01),and the probability of occurrence of amniotic opacity in IDA pregnant women with damp-heat constitution was significantly higher than that in IDA pregnant women with balanced constitution and other biased constitution types(P<0.05).Conclusion Damp-heat constitution is the most common TCM constitution type in pregnant women with IDA,followed by yang deficiency constitution,yin deficiency constitution and qi deficiency constitution.The damp-heat constitution may be the susceptible constitution of pregnant women with IDA,and IDA pregnant women with damp-heat constitution have significantly higher Fer level than those with balanced constitution,and also have the higher probability of occurrence of amniotic opacity than those with balanced constitution and other biased constitution types.

iron deficiency anemiapregnancytraditional Chinese medicine(TCM)constitutiondamp-heat constitutionserum ferritinpregnancy outcomesamniotic opacity

王颖、周静文、杨烨耀、苏丽珊、李艳芳

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广州中医药大学第一临床医学院,广东广州 510405

广州中医药大学第一附属医院产科,广东广州 510405

缺铁性贫血 妊娠期 中医体质 湿热质 血清铁蛋白 妊娠结局 羊水混浊

国家自然科学基金项目广东省科技计划项目

817041112017ZC0150

2024

广州中医药大学学报
广州中医药大学

广州中医药大学学报

CSTPCD
影响因子:1.055
ISSN:1007-3213
年,卷(期):2024.41(1)
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