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柴平汤联合脐灸治疗肝郁脾虚证腹泻型肠易激综合征的临床观察

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[目的]观察柴平汤联合脐灸治疗肝郁脾虚证腹泻型肠易激综合征的临床疗效.[方法]将62例肝郁脾虚证腹泻型肠易激综合征患者随机分为观察组和对照组,每组各31例.观察组给予柴平汤联合脐灸治疗,对照组给予匹维溴铵片治疗,连续治疗4周.治疗1个月后,评价2组患者的临床疗效,观察2组患者治疗前后中医证候积分、肠易激综合征症状严重程度量表(IBS-SSS)评分以及肠易激综合征生活质量量表(IBS-QOL)评分的变化情况,并评价2组患者的复发情况和安全性.[结果](1)治疗后,2组患者的中医证候积分、IBS-SSS评分、IBS-QOL评分均明显改善(P<0.05),且观察组在改善中医证候积分、IBS-SSS评分、IBS-QOL评分方面均明显优于对照组,差异均有统计学意义(P<0.05).(2)观察组总有效率为90.32%(28/31),对照组为74.19%(23/31),观察组疗效优于对照组,差异有统计学意义(P<0.05).(3)治疗结束后12周随访,观察组的复发率为14.29%(4/28),对照组为47.83%(11/23),观察组的复发率低于对照组,差异有统计学意义(P<0.05).(4)治疗期间,2组患者均未出现水泡、烫伤、疼痛等不良反应,且患者的各项安全指标均在正常范围内.[结论]柴平汤联合脐灸治疗肝郁脾虚证腹泻型肠易激综合征,能明显改善患者的临床症状,从而提高患者生活质量,疗效显著.
Clinical Observation on the Chaiping Decoction Combined with Umbilical Moxibustion in the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome with Liver Depression and Spleen Deficiency Syndrome
Objective To observe the clinical efficacy of Chaiping Decoction combined with umbilical moxibustion in the treatment of diarrhea-predominant irritable bowel syndrome(IBS-D)with liver depression and spleen deficiency syndrome.Methods A total of 62 patients with liver depression and spleen deficiency syndrome of IBS-D were randomly divided into the observation group and control group,31 cases in each group.The observation group was treated with Chaiping Decoction combined with umbilical moxibustion,and the control group was treated with Pinaverium Bromide Tablets for four weeks.After one month of treatment,the clinical efficacy of the two groups was evaluated.The changes of TCM syndrome scores,Irritable Bowel Syndrome Symptom Severity Scale(IBS-SSS)scores and Irritable Bowel Syndrome Quality Of Life Scale(IBS-QOL)scores were observed before and after treatment in the two groups,and the recurrence and safety of the two groups were evaluated.Results(1)After treatment,TCM syndrome scores,IBS-SSS scores,and IBS-QOL scores in the two groups were significantly improved(P<0.05),and the improvement of TCM syndrome scores,IBS-SSS scores,and IBS-QOL scores in the observation group was superior to that in the control group,differences being significant(P<0.05).(2)The total effective rate was 90.32%(28/31)in the observation group and 74.19%(23/31)in the control group.The curative effect of the observation group was superior to that of the control group,and the difference was statistically significant(P<0.05).(3)After 12 weeks of treatment,the recurrence rate of the observation group was 14.29%(4/28),and that of the control group was 47.83%(11/23).The recurrence rate of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).(4)During the treatment,no adverse reactions such as blisters,scalds and pain occurred in the two groups,and the safety indexes of the patients were within the normal range.Conclusion Chaiping Decoction combined with umbilical moxibustion in the treatment of liver depression and spleen deficiency type of IBS-D can significantly improve the clinical symptoms of patients,thereby improving the quality of life of patients,and the curative effect is significant.

diarrhea-predominant irritable bowel syndrome(IBS-D)liver depression and spleen deficiency syndromeChaiping Decoctionumbilical moxibustionquality of lifeclinical observation

王盼、毛妮、吴凡伟

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广州中医药大学第七临床医学院/深圳市宝安中医院,广东深圳 518100

广州中医药大学研究生院,广东广州 510006

腹泻型肠易激综合征 肝郁脾虚证 柴平汤 脐灸 生活质量 临床观察

2024

广州中医药大学学报
广州中医药大学

广州中医药大学学报

CSTPCD
影响因子:1.055
ISSN:1007-3213
年,卷(期):2024.41(8)
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