Objective To observe the clinical efficacy of acupuncture combined with Zi Yu Bushen Yiqi Tiaojing Decoction in the treatment of polycystic ovary syndrome(PCOS)and its effect on ovarian reserve function and sex hormone level.Methods Sixty patients with PCOS of phlegm-damp due to kidney deficiency type were randomly divided into observation group and control group,30 patients in each group,the control group was treated with conventional western medicines,and the observation group was treated with acupuncture combined with Zi Yu Bushen Yiqi Tiaojing Decoction on the basis of treatment of the control group.Both groups were treated for six months.After six months of treatment,the clinical efficacy of the two groups was evaluated,and the changes of traditional Chinese medicine(TCM)syndrome scores and the levels of testosterone(T),luteinizing hormone(LH)and follicle stimulating hormone(FSH)of the two groups of patients were observed before and after treatment.The changes of anti-Mullerian hormone(AMH),antral follicle count(AFC),as well as endometrial thickness,ovarian volume and cervical score before and after treatment between the two groups of patients were compared.The safety of the two groups and the natural pregnancy rate after one year follow-up were evaluated.Results(1)After treatment,the TCM syndrome scores of patients in the two groups were significantly improved(P＜0.05),and the improvement in the observation group was significantly superior to that in the control group,and the differences were all statistically significant(P＜0.05).(2)After treatment,the AFC and AMH levels of patients in the two groups were improved significantly(P＜0.05),and the improvement in the observation group was significantly superior to that in the control group,and the difference was statistically significant(P＜0.05).(3)After treatment,the levels of T,LH and FSH of patients in the two groups were improved significantly(P＜0.05),and the improvement in the observation group was significantly superior to that in the control group,with statistically significant differences(P＜0.05).(4)After treatment,the endometrial thickness,ovarian volume,and cervical score of patients in the two groups were significantly improved(P＜0.05),and the improvement in the observation group was significantly superior to that in the control group,with statistically significant differences(P＜0.05).(5)The total effective rate was 96.67%(29/30)in the observation group and 73.33%(22/30)in the control group.The efficacy of the observation group was superior to that of the control group,and the difference was statistically significant(P＜0.05).(6)The incidence of adverse reactions during the treatment period in the observation group and the control group was 6.67%(2/30)and 33.33%(10/30)respectively,the difference was not statistically significant(P＞0.05).After one year follow-up,the natural pregnancy rate in the observation group and the control group was 60.00%(18/30)and 33.33%(10/30)respectively,and the natural pregnancy rate in the observation group was significantly higher than that in the control group,the difference was statistically significant(P＜0.05).Conclusion Acupuncture combined with Zi Yu Bushen Yiqi Tiaojing Decoction in treating PCOS can significantly improve the clinical symptoms of patients,enhance the reserve function of the ovaries,promote the recovery of sex hormone levels and recovery of uterus,and increase the pregnancy rate,with remarkable clinical efficacy.
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