红姜花中黄酮的分离与鉴定
Isolation and Identification of Flavonoids from Hedychium coccineum
郑丽 1周日海 1张婉婷 1张金凤 1彭伟 1陈业高1
作者信息
- 1. 云南师范大学 化学化工学院,云南 昆明 650500
- 折叠
摘要
风干粉碎后的红姜花(Hedychium coccineum)根茎用工业甲醇浸提,甲醇浸提物用乙酸乙酯-水萃取.采用多种分离技术(硅胶柱层析、Sephadex LH-20、RP-18柱层析、HPLC)分离乙酸乙酯浸膏中的化学成分,通过NMR等方法对所得的化合物进行结构鉴定.共鉴定6个黄酮类化合物,分别是 5-hydroxy-3,7,4'-trimethoxyflavone(1)、3,5-dihydroxy-7,4'-dimethoxyflavone(2)、kaempferol-4'-O-methylether(3)、ermanin(4)、dihydrokaempferide(5)、aromadendrin-7,4'-dimethyl ether(6).均为首次从红姜花中分离得到.
Abstract
The air-dried and crushed rhizomes of Hedychium coccineum were extracted with MeOH,and the extract was partitioned with EtOAc-H2O.The EtOAc extract was isolated by various separation techniques(Silica gel,Sephadex LH-20,RP-18 column chromatography and HPLC).By means of spectroscopic analysis,the isolated compounds were identi-fied as 5-hydroxy-3,7,4'-trimethoxyflavone(1),3,5-dihydroxy-7,4'-dimethoxyflavone(2),kaempferol-4'-O-methylether(3),ermanin(4),dihydrokaempferide(5)and aromadendrin-7,4'-dimethyl ether(6).All the compounds were isolated from H.coccineum for the first time.
关键词
红姜花/化学成分/黄酮Key words
Hedychium coccineum/chemical constituent/flavonoid引用本文复制引用
基金项目
云南省高等学校药用活性分子结构多样性研究重点实验室项目()
云南师范大学大学生科研训练基金(KX2022022)
出版年
2024
国家科技期刊平台
NSTL
万方数据