云南巴豆中倍半萜类化合物的研究
Study on Sesquiterpenoids from Croton yunnanensis
谢志胥 1余梅 1杨舜伊 1安倩玉 1陈业高1
作者信息
- 1. 云南师范大学 化学化工学院,云南 昆明 650500
- 折叠
摘要
云南巴豆(Croton yunnanensis)枝叶风干粉碎后用甲醇提取,使用硅胶柱层析、MCI柱层析、Sephadex LH-20凝胶柱层析及HPLC等分离技术对其化学成分进行分离纯化,得到5个倍半萜类化合物,分别是(-)-ent-6α-methoxyeudesm-4(15)-en-1β-ol(1),oplodiol(2),(7R*)-opposit-4(15)-ene-1 β,7-diol(3),aphanamol I(4)和 orientalol C(5).化合物 1-4 为首次从该种植物中分离得到.
Abstract
The branches and leaves of Croton yunnanensis were dried and extracted with methanol.The chemical compo-nents were separated and purified by silica gel column chromatography,MCI column chromatography,Sephadex LH-20 gel column chromatography and HPLC.These compounds were identified as(-)-ent-6α-methoxyeudesm-4(15)-en-1β-ol(1),oplodiol(2),(7R*)-opposit-4(15)-ene-1β,7-diol(3),aphanamol I(4)and orientalol C(5).Compounds 1-4 were isolated from this plant for the first time.
关键词
云南巴豆/倍半萜类化合物/化学成分/结构鉴定Key words
Croton yunnanensis/sesquiterpenoids/chemical constituents/structural identification引用本文复制引用
基金项目
云南省高等学校药用活性分子结构多样性研究重点实验室项目()
出版年
2024
国家科技期刊平台
NSTL
万方数据