With the increasing incidence of diabetes,diabetic kidney disease(DKD)has become the primary reason of chronic nephrosis and end-stage renal disease over the world.However,recent drugs,aiming to control the blood glucose level and inhibit the renin-angiotensin system,can't prevent the developing of DKD.Recent research has indicated that Chronic low-grade inflam-mation and activation of immune system play important role in occurrence and development of DKD.Understanding the inflamma-tory cascade in DKD progression and its mechanisms will help identify new potential targets and help design innovative anti-inflam-matory based therapeutic strategies.In recent years,more and more evidence has shown that traditional Chinese medicine can de-lay the progression of end-stage renal disease in the treatment of inflammation.Based on the mechanism of inflammation,we re-view the protective effects of TCM monomers DKD-induced kidney injury,which provides a new idea for the research and devel-opment of new drugs for the treatment of inflammatory diseases and related mechanisms.
关键词
糖尿病肾病/炎症/中药单体
Key words
Diabetic kidney disease/Inflammation/Monomer of Chinese traditional herbs
维普
万方数据