Research progress of TCM monomer in treating diabetic kidney disease based on inflammatory mechanism
With the increasing incidence of diabetes,diabetic kidney disease(DKD)has become the primary reason of chronic nephrosis and end-stage renal disease over the world.However,recent drugs,aiming to control the blood glucose level and inhibit the renin-angiotensin system,can't prevent the developing of DKD.Recent research has indicated that Chronic low-grade inflam-mation and activation of immune system play important role in occurrence and development of DKD.Understanding the inflamma-tory cascade in DKD progression and its mechanisms will help identify new potential targets and help design innovative anti-inflam-matory based therapeutic strategies.In recent years,more and more evidence has shown that traditional Chinese medicine can de-lay the progression of end-stage renal disease in the treatment of inflammation.Based on the mechanism of inflammation,we re-view the protective effects of TCM monomers DKD-induced kidney injury,which provides a new idea for the research and devel-opment of new drugs for the treatment of inflammatory diseases and related mechanisms.
Diabetic kidney diseaseInflammationMonomer of Chinese traditional herbs