Risk factors for delirium in elderly patients after hip fracture surgery:A meta-analysis
Objective:To determine the risk factors of delirium in elderly patients after hip fracture surgery.Methods:We searched electronic bibliograp-hic databases for eligible original studies published until November 2022.After literature screening,data extraction and quality evaluation,meta-analysis was performed using Stata17.0 and RevMan5.4.Results:A total of 16 studies were included,The incidence of delirium in elderly patients with hip fracture was 23.0%[95%CI=(20%~26%)].The main risk factors for perioperative delirium in elderly patients with hip fracture were advanced age[OR=1.24,95%CI=(1.10-1.40),P<0.001],pain[OR=2.01,95%CI=(1.48-2.75),P<0.001],stroke history[OR=5.22,95%CI=(2.75-9.92),P<0.001],compli-cations≥3[OR=2.25,95%CI=(1.33-3.81),P=0.002],preoperative cognitive dysfunction[OR=3.45,95%CI=(2.51-4.75),P<0.001],hypoxemia[OR=3.91,95%CI=(2.70-5.67),P<0.001],long preoperative wait time[OR=3.98,95%CI=(1.16-13.98),P=0.030],general anesthesia[OR=2.55,95%CI=(1.81-3.59),P<0.001],long operation time[OR=1.61,95%CI=(1.22-2.11),P<0.001],preoperative low albumin[OR=6.42,95%CI=(2.59-15.88),P<0.001],low BMI[OR= 3.06,95%CI=(1.71-5.46),P<0.001].Conclusion:The incidence of postoperation delirium in elderly patients of hip fracture is high and there are many influencing factors.Early screening and intervention for delirium risk should be carried out to reduce the impact of adverse outcomes on patients.
Hip fracturePerioperative periodDeliriumRisk factorsMeta-analysis