Meta-analysis of risk factors associated with dysphagia after anterior cervical spine surgeries
Objective:To apply evidence-based medicine for systematically evaluating the risk factors for dysphagia after ante-rior cervical spine surgeries.Methods:Relevant papers included were retrieved with a time range from the establishment of the da-tabasis to July 1st,2023 from databases including CNKI,CBM,VIP,Wanfang database,The Cochrane Library,Embase,PubMed and collected case-control studies and cohort studies of risk factors for dysphagia after anterior cervical spine surgeries.Newcastle-Ottawa Scale was used to extracted research data and evaluated the quality of the included literature,then use the Rev-Man5.4 statistical software for meta-analysis evaluation.Results:A total of 29 papers and 7 487 patients were included in this anal-ysis,1 640 patients of whom developed dysphagia.And the Meta analysis of the data showed that female[OR=2.93,95%CI(2.45,3.51),P<0.000 01],age[MD=5.82,95%CI(3.91,7.73),P<0.000 01],smoking[OR=2.48,95%CI(1.89,3.27),P<0.000 01],diabetes[OR=2.41,95%CI(1.41,4.12),P=0.001],surgical level≥2 level[OR=2.10,95%CI(1.73,2.56),P<0.000 01],surgical segment location[OR=2.21,95%CI(1.64,2.98),P<0.000 01],operation time[MD=24.73,95%CI(14.66,34.79),P<0.000 01],use of plate[OR=5.93,95%CI(3.62,9.71),P<0.000 01],postoperative prevertebral soft tis-sue swelling[MD=1.77,95%CI(0.04,3.50),P=0.04],dC2-7Cobb angle[MD=2.36,95%CI(1.34,3.37),P<0.000 01]are risk factors for dysphagia after anterior cervical spine surgeries;preoperative tracheal stretch exercise[OR=0.26,95%CI(0.17,0.41),P<0.000 01]are protective factors for dysphagia after anterior cervical spine surgeries;there was no statistically significant association between postoperative 0-C2 angle[MD=-1.65,95%CI(-5.05,1.76),P=0.34],postoperative C2-7Cobb angle[MD=3.45,95%CI(-0.07,6.98),P=0.05]and dysphagia after anterior cervical spine surgeries.Conclusion:Female,age,smoking,diabetes,surgical level≥2 level,surgical segment location,operation time,use of plate,postoperative prevertebral soft tissue swelling,and dC2-7Cobb angle are risk factors for dysphagia after anterior cervical spine surgeries,preoperative tracheal stretch ex-ercise is protective factor for dysphagia after anterior cervical spine surgeries.According to these factors,doctors can communicate with patients about the possibility of postoperative dysphagia in advance,prevent postoperative dysphagia and reduce the occur-rence of postoperative dysphagia.
万方数据
维普
