海南医学院学报2024,Vol.30Issue(11) :873-880.DOI:10.13210/j.cnki.jhmu.20231121.001

妊娠期阴道微生态与妊娠结局相关性研究进展

Progress in the relationship between vaginal microbiome and pergnancy outcomes in pregnant females

徐小惠 马宁 卢伟英
海南医学院学报2024,Vol.30Issue(11) :873-880.DOI:10.13210/j.cnki.jhmu.20231121.001

妊娠期阴道微生态与妊娠结局相关性研究进展

Progress in the relationship between vaginal microbiome and pergnancy outcomes in pregnant females

徐小惠 1马宁 2卢伟英2
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作者信息

  • 1. 海南省妇女儿童医学中心产科,海南 海口 570312;海南医学院附属儿童医院,海南 海口 571199
  • 2. 海南省妇女儿童医学中心生殖中心,海南 海口 570312;海南医学院附属儿童医院,海南 海口 571199
  • 折叠

摘要

健康的育龄女性阴道内存在的微生物种类繁多,其中乳酸杆菌为主要菌群,是维持阴道微生态平衡的重要角色.当阴道内的酸碱度失衡、菌群结构紊乱、局部免疫功能下降等情况发生时,阴道微生态平衡则容易被破坏,甚至发生阴道感染.阴道微生态紊乱不仅影响女性生活质量,还与女性妊娠期的不良妊娠结局存在相关性,影响母婴健康.因此,本文就妊娠期阴道微生态情况及其与妊娠结局相关性研究进展做一综述.

Abstract

The vaginal microbiota of healthy women of reproductive age is characterized by a wide variety of microorganisms,with Lactobacilli being the predominant group.Lactobacilli play an important role in maintaining the balance of vaginal microbio-ta.When there is an imbalance in the acidity and alkalinity of the vagina,a structural disorder in the bacterial community,or a de-crease in local immune function,the balance of the vaginal microbiota is easily disrupted,and even vaginal infections occur.The disturbance of vaginal microbiota not only affects women's quality of life,but also has a correlation with adverse perinatal outcomes during pregnancy,affecting maternal and fetal health.Therefore,this article provides a comprehensive review of the research on the vaginal microbiota during pregnancy and its correlation with perinatal outcomes.

关键词

妊娠期/阴道微生态/妊娠结局

Key words

Pregnancy/Vaginal microbiota/Perinatal outcomes

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基金项目

国家自然科学基金(82260304)

海南省重点研发计划(ZDYF2022SHFZ074)

出版年

2024
海南医学院学报
海南医学院

海南医学院学报

CSTPCD北大核心
影响因子:1.068
ISSN:1007-1237
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