目的:运用网状Meta分析中成药联合西医常规治疗围绝经期女性情绪障碍的疗效和安全性。方法:检索中国知网(CNKI)、维普(VIP)数据库、万方(Wanfang)、中国生物医学文献服务系统(SinoMed)、Cochrane Library、PubMed、Embase、Web of Science数据库，获取中成药治疗围绝经期情绪障碍的随机对照试验，使用RevMan 5。4和Stata 15进行统计学分析。结果:网状Meta示:在提高临床有效率方面，舒肝颗粒联合西医常规治疗最佳;在降低HAMD方面，丹栀逍遥丸联合西医常规治疗最佳;在降低HAMA方面，坤泰胶囊联合西医常规治疗最佳;在降低KI方面，乌灵胶囊联合西医常规治疗最佳;在调节性激素方面，坤泰胶囊联合西医常规治疗最佳;在降低不良反应方面，血府逐瘀胶囊/口服液联合西医常规治疗最佳。结论:中成药联合西医常规治疗围绝经期女性情绪障碍有效且各有优势，但由于纳入文献数量和质量的限制，今后仍需进行更高质量的分析。
Network meta-analysis of Chinese patent medicine combined with conventional western medicine in treatment of Emotional Disorder in Perimenopausal Women
Objective:To evaluate the efficacy and safety of Chinese patent medicine combined with conventional western medicine in the treatment of emotional disorder in perimenopausal women.Methods:CNKI,VIP,Wanfang,SinoMed,Co-chrane Library,PubMed,Embase,Web of Science were retrieved to acquire randomized controlled trials of Chinese patent medi-cine in the treatment of emotional disorder in perimenopausal women.RevMan 5.4 and Stata 15 were used to analyze the data.Re-sults:Network meta-analysis showed that in the aspect of improve clinical effective,Shugan granule combined with conventional western medicine treatment had the best effect.In the aspect of reducing HAMD,Danzhi Xiaoyao pill combined with conventional western medicine treatment had the best effect.In the aspect of reducing HAMA,Kuntai capsule combined with conventional western medicine treatment had the best effect.In the aspect of reducing KI,Wuling capsule combined with conventional western medicine treatment had the best effect.In the aspect of regulate sex hormone,Kuntai capsules with conventional Western medicine treatment had the best effect.In the aspect of reducing adverse reactions,Xuefuzhuyu capsule/oral liquid with conventional West-ern medicine treatment had the best effect.Conclusion:Chinese patent medicines with conventional Western medicine are effective in the treatment of emotional disorder in perimenopausal women and each has its own advantages.However,due to the limitations of the quantity and quality of the included literatures,higher quality studies are needed in the future.
国家科技期刊平台
NSTL
万方数据
